Hypernatrémie chez le patient cérébrolésé: Utile ou dangereux?

Translated title of the contribution: Hypernatremia in head-injured patients: Friend or foe?

J. F. Payen, P. Bouzat, G. Francony, C. Ichai

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Hypernatremia is defined by a serum sodium concentration of more than 145. mmol/L and reflects a disturbance of the regulation between water and sodium. The high incidence of hypernatremia in patients with severe brain injury is due various causes including poor thirst, diabetes insipidus, iatrogenic sodium administration, and primary hyperaldosteronism. Hypernatremia in the intensive care unit is independently associated with increased mortality and complications rates. Because of the rapid brain adaptation to extracellular hypertonicity, sustained hypernatremia exposes the patient to an exacerbation of brain edema during attempt to normalize natremia. Like serum glucose, serum sodium concentration must be tightly monitored in the intensive care unit.

Translated title of the contributionHypernatremia in head-injured patients: Friend or foe?
Original languageFrench
Pages (from-to)433-435
Number of pages3
JournalAnnales Francaises d'Anesthesie et de Reanimation
Issue number6
StatePublished - Jun 2014


  • Head injury
  • Hypernatremia
  • Intensive care
  • Osmotherapy
  • Serum sodium concentration

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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