Hypercalcemia in small cell carcinoma of the pancreas

R. D. Hobbs, A. F. Stewart, N. D. Ravin, D. Carter

Research output: Contribution to journalArticlepeer-review

Abstract

Although small cell carcinoma of the lung has a high incidence of skeletal metastasis and is frequently associated with paraneoplastic syndromes, it is only rarely associated with hypercalcemia. Similarly, the more unusual small cell carcinoma of the pancreas has not been associated with hypercalcemia. The authors describe the first such patient with small cell carcinoma of the pancreas and hypercalcemia. Comprehensive metabolic measurements (fasting calcium excretion, renal phosphorus threshold, 1,25 dihydroxyvitamin D, 25 hydroxyvitamin D levels, nephrogenous cyclic AMP and immunoreactive PTH levels) suggest that although bone metastases were present, the hypercalcemia may have been caused on part by humoral mechanisms.

Original languageEnglish (US)
Pages (from-to)1552-1554
Number of pages3
JournalCancer
Volume53
Issue number7
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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