Hybrid natural orifice translumenal surgery (NOTES) sleeve gastrectomy: A feasibility study using an animal model

Yoav Mintz, Santiago Horgan, Michelle K. Savu, John Cullen, Alana Chock, Sonia Ramamoorthy, David W. Easter, Mark A. Talamini

Research output: Contribution to journalArticle

Abstract

Background: The indications for natural orifice translumenal surgery (NOTES) are yet to be determined. Morbidly obese patients may be one population that would benefit from this approach due to the elimination of wound complications and possibly a faster recovery. As a bariatric restrictive procedure, sleeve gastrectomy could be one indication for NOTES. To test the feasibility of this procedure with a NOTES approach, a pig model was used. Methods: Acute studies investigated five 40-kg farm pigs. The rectum was used as the port of entry to the peritoneal cavity, and the stomach was manipulated endoluminally using a gastroscope. Vision was acquired through a 5-mm laparoscope introduced transabdominally (i.e. via the hybrid technique). A 10-mm incision was made on the anterior wall of the rectum and dilated to accommodate a 12-mm trocar introduced through the rectal wall into the peritoneal cavity. The greater curvature of the stomach then was divided and detached, starting from the antrum and proceeding to the esophagogastric junction using a laparoscopic stapler. The sleeve gastrectomy was completed by dividing the short gastric vessels with an ultrasonic scalpel. The gastric pouch then was removed through the rectal incision. Results: A NOTES gastric sleeve resection was successfully performed in all five pigs. The technique was developed, and feasibility was determined. After resection, the gastric remnant was inflated, with no evidence of leakage. At autopsy, intact suture lines were noted. Closure of the rectal incision was not attempted. Conclusion: A NOTES sleeve gastrectomy is feasible in porcine animal models. The rectal port of entry allows rigid laparoscopic instruments to be introduced into the peritoneal cavity and enables performance of gastrointestinal procedures the same as in standard laparoscopic surgery. Extra-long instruments are necessary for dissection and division of the stomach at the esophagogastric junction and for accessing the short gastric vessels.

Original languageEnglish (US)
Pages (from-to)1798-1802
Number of pages5
JournalSurgical Endoscopy and Other Interventional Techniques
Volume22
Issue number8
DOIs
StatePublished - Aug 2008
Externally publishedYes

Fingerprint

Feasibility Studies
Gastrectomy
Stomach
Animal Models
Peritoneal Cavity
Swine
Esophagogastric Junction
Rectum
Gastroscopes
Laparoscopes
Gastric Stump
Bariatrics
Surgical Instruments
Ultrasonics
Laparoscopy
Sutures
Dissection
Autopsy
Wounds and Injuries
Population

Keywords

  • Bariatric surgery
  • Gastrectomy
  • NOTES
  • Restrictive
  • Sleeve

ASJC Scopus subject areas

  • Surgery

Cite this

Hybrid natural orifice translumenal surgery (NOTES) sleeve gastrectomy : A feasibility study using an animal model. / Mintz, Yoav; Horgan, Santiago; Savu, Michelle K.; Cullen, John; Chock, Alana; Ramamoorthy, Sonia; Easter, David W.; Talamini, Mark A.

In: Surgical Endoscopy and Other Interventional Techniques, Vol. 22, No. 8, 08.2008, p. 1798-1802.

Research output: Contribution to journalArticle

Mintz, Yoav ; Horgan, Santiago ; Savu, Michelle K. ; Cullen, John ; Chock, Alana ; Ramamoorthy, Sonia ; Easter, David W. ; Talamini, Mark A. / Hybrid natural orifice translumenal surgery (NOTES) sleeve gastrectomy : A feasibility study using an animal model. In: Surgical Endoscopy and Other Interventional Techniques. 2008 ; Vol. 22, No. 8. pp. 1798-1802.
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abstract = "Background: The indications for natural orifice translumenal surgery (NOTES) are yet to be determined. Morbidly obese patients may be one population that would benefit from this approach due to the elimination of wound complications and possibly a faster recovery. As a bariatric restrictive procedure, sleeve gastrectomy could be one indication for NOTES. To test the feasibility of this procedure with a NOTES approach, a pig model was used. Methods: Acute studies investigated five 40-kg farm pigs. The rectum was used as the port of entry to the peritoneal cavity, and the stomach was manipulated endoluminally using a gastroscope. Vision was acquired through a 5-mm laparoscope introduced transabdominally (i.e. via the hybrid technique). A 10-mm incision was made on the anterior wall of the rectum and dilated to accommodate a 12-mm trocar introduced through the rectal wall into the peritoneal cavity. The greater curvature of the stomach then was divided and detached, starting from the antrum and proceeding to the esophagogastric junction using a laparoscopic stapler. The sleeve gastrectomy was completed by dividing the short gastric vessels with an ultrasonic scalpel. The gastric pouch then was removed through the rectal incision. Results: A NOTES gastric sleeve resection was successfully performed in all five pigs. The technique was developed, and feasibility was determined. After resection, the gastric remnant was inflated, with no evidence of leakage. At autopsy, intact suture lines were noted. Closure of the rectal incision was not attempted. Conclusion: A NOTES sleeve gastrectomy is feasible in porcine animal models. The rectal port of entry allows rigid laparoscopic instruments to be introduced into the peritoneal cavity and enables performance of gastrointestinal procedures the same as in standard laparoscopic surgery. Extra-long instruments are necessary for dissection and division of the stomach at the esophagogastric junction and for accessing the short gastric vessels.",
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T2 - A feasibility study using an animal model

AU - Mintz, Yoav

AU - Horgan, Santiago

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AU - Cullen, John

AU - Chock, Alana

AU - Ramamoorthy, Sonia

AU - Easter, David W.

AU - Talamini, Mark A.

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AB - Background: The indications for natural orifice translumenal surgery (NOTES) are yet to be determined. Morbidly obese patients may be one population that would benefit from this approach due to the elimination of wound complications and possibly a faster recovery. As a bariatric restrictive procedure, sleeve gastrectomy could be one indication for NOTES. To test the feasibility of this procedure with a NOTES approach, a pig model was used. Methods: Acute studies investigated five 40-kg farm pigs. The rectum was used as the port of entry to the peritoneal cavity, and the stomach was manipulated endoluminally using a gastroscope. Vision was acquired through a 5-mm laparoscope introduced transabdominally (i.e. via the hybrid technique). A 10-mm incision was made on the anterior wall of the rectum and dilated to accommodate a 12-mm trocar introduced through the rectal wall into the peritoneal cavity. The greater curvature of the stomach then was divided and detached, starting from the antrum and proceeding to the esophagogastric junction using a laparoscopic stapler. The sleeve gastrectomy was completed by dividing the short gastric vessels with an ultrasonic scalpel. The gastric pouch then was removed through the rectal incision. Results: A NOTES gastric sleeve resection was successfully performed in all five pigs. The technique was developed, and feasibility was determined. After resection, the gastric remnant was inflated, with no evidence of leakage. At autopsy, intact suture lines were noted. Closure of the rectal incision was not attempted. Conclusion: A NOTES sleeve gastrectomy is feasible in porcine animal models. The rectal port of entry allows rigid laparoscopic instruments to be introduced into the peritoneal cavity and enables performance of gastrointestinal procedures the same as in standard laparoscopic surgery. Extra-long instruments are necessary for dissection and division of the stomach at the esophagogastric junction and for accessing the short gastric vessels.

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