The role of humoral and cellular immunity in experimental autoimmune thyroiditis was examined in inbred rat strains. A significant relationship between thyroiditis and both in vitro proliferative responses to rat thyroglobulin and in vivo delayed hypersensitivity (ear test) was observed in responsive rats. Comparison of the autoantibody response and thyroiditis among rat strains revealed no direct correlation of RT1 genotype with either parameter.
|Original language||English (US)|
|Number of pages||9|
|Journal||Clinical and Experimental Immunology|
|State||Published - Jan 1 1982|
ASJC Scopus subject areas
- Immunology and Allergy