Humoral and cellular immune response to thyroglobulin in different inbred rat strains

H. S. Lillehoj, N. R. Rose

Research output: Contribution to journalArticle

Abstract

The role of humoral and cellular immunity in experimental autoimmune thyroiditis was examined in inbred rat strains. A significant relationship between thyroiditis and both in vitro proliferative responses to rat thyroglobulin and in vivo delayed hypersensitivity (ear test) was observed in responsive rats. Comparison of the autoantibody response and thyroiditis among rat strains revealed no direct correlation of RT1 genotype with either parameter.

Original languageEnglish (US)
Pages (from-to)661-669
Number of pages9
JournalClinical and Experimental Immunology
Volume47
Issue number3
Publication statusPublished - 1982
Externally publishedYes

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ASJC Scopus subject areas

  • Immunology

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