Humoral and cellular immune response to thyroglobulin in different inbred rat strains

H. S. Lillehoj; N. R. Rose

Humoral and cellular immune response to thyroglobulin in different inbred rat strains

H. S. Lillehoj, N. R. Rose

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

The role of humoral and cellular immunity in experimental autoimmune thyroiditis was examined in inbred rat strains. A significant relationship between thyroiditis and both in vitro proliferative responses to rat thyroglobulin and in vivo delayed hypersensitivity (ear test) was observed in responsive rats. Comparison of the autoantibody response and thyroiditis among rat strains revealed no direct correlation of RT1 genotype with either parameter.

Original language	English (US)
Pages (from-to)	661-669
Number of pages	9
Journal	Clinical and Experimental Immunology
Volume	47
Issue number	3
State	Published - Jan 1 1982

ASJC Scopus subject areas

Immunology and Allergy
Immunology

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abstract = "The role of humoral and cellular immunity in experimental autoimmune thyroiditis was examined in inbred rat strains. A significant relationship between thyroiditis and both in vitro proliferative responses to rat thyroglobulin and in vivo delayed hypersensitivity (ear test) was observed in responsive rats. Comparison of the autoantibody response and thyroiditis among rat strains revealed no direct correlation of RT1 genotype with either parameter.",

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