Human t–cell lymphotropic virus infection among blood donors in south florida

Wade P. Parks, Bruce A. Lenes, Peter A. Tomasulo, Eugene R. Schiff, Elizabeth S. Parks, George M. Shaw, Helen Lee, Hui Qin Yan, Shenghan Lai, Charles G. Hollingsworth, George J. Nemo, James W. Mosley

Research output: Contribution to journalArticle

Abstract

Knowledge of the epidemiologic pattern of human T–lymphotropic virus (HTLV) in the United States is being enlarged by blood donor screening. We tested stored sera from 29,937 donations made in South Florida in 1984–1985. Twenty–three donors were confirmed as seropositive, a prevalence of 0.8 per 1,000 donations. Specificity was supported by serologic retesting and virus culture of 11 donors located for follow–up. Sex–and age–specific prevalences did not differ significantly; blacks, however, accounted for 65% of seropositive donations. Within South Florida, one section of Miami had a prevalence of 4.5 per 1,000 donations, significantly above the 0.1 to 1.1 per 1,000 rates for other parts. An epidemiologic association with known HTLV–I endemic areas could account for most infections; all seven typed isolates were characterized as HTLV–I. Exposures, however, were diverse, sometimes multiple, and had no necessary relationship to personal lifestyle. This finding suggests that sources of infection were varied. Seropositive family members emphasize familial clustering of HTLV–I infection.

Original languageEnglish (US)
Pages (from-to)89-96
Number of pages8
JournalJournal of Acquired Immune Deficiency Syndromes
Volume4
Issue number1
StatePublished - 1991
Externally publishedYes

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Virus Diseases
Blood Donors
Infection
Tissue Donors
Viruses
Donor Selection
Cluster Analysis
Life Style
Serum

Keywords

  • Blood donors
  • Blood transfusion
  • Cross–sectional studies
  • Htlv infections

ASJC Scopus subject areas

  • Infectious Diseases
  • Pharmacology (medical)
  • Immunology and Allergy
  • Virology

Cite this

Parks, W. P., Lenes, B. A., Tomasulo, P. A., Schiff, E. R., Parks, E. S., Shaw, G. M., ... Mosley, J. W. (1991). Human t–cell lymphotropic virus infection among blood donors in south florida. Journal of Acquired Immune Deficiency Syndromes, 4(1), 89-96.

Human t–cell lymphotropic virus infection among blood donors in south florida. / Parks, Wade P.; Lenes, Bruce A.; Tomasulo, Peter A.; Schiff, Eugene R.; Parks, Elizabeth S.; Shaw, George M.; Lee, Helen; Yan, Hui Qin; Lai, Shenghan; Hollingsworth, Charles G.; Nemo, George J.; Mosley, James W.

In: Journal of Acquired Immune Deficiency Syndromes, Vol. 4, No. 1, 1991, p. 89-96.

Research output: Contribution to journalArticle

Parks, WP, Lenes, BA, Tomasulo, PA, Schiff, ER, Parks, ES, Shaw, GM, Lee, H, Yan, HQ, Lai, S, Hollingsworth, CG, Nemo, GJ & Mosley, JW 1991, 'Human t–cell lymphotropic virus infection among blood donors in south florida', Journal of Acquired Immune Deficiency Syndromes, vol. 4, no. 1, pp. 89-96.
Parks WP, Lenes BA, Tomasulo PA, Schiff ER, Parks ES, Shaw GM et al. Human t–cell lymphotropic virus infection among blood donors in south florida. Journal of Acquired Immune Deficiency Syndromes. 1991;4(1):89-96.
Parks, Wade P. ; Lenes, Bruce A. ; Tomasulo, Peter A. ; Schiff, Eugene R. ; Parks, Elizabeth S. ; Shaw, George M. ; Lee, Helen ; Yan, Hui Qin ; Lai, Shenghan ; Hollingsworth, Charles G. ; Nemo, George J. ; Mosley, James W. / Human t–cell lymphotropic virus infection among blood donors in south florida. In: Journal of Acquired Immune Deficiency Syndromes. 1991 ; Vol. 4, No. 1. pp. 89-96.
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