TY - JOUR
T1 - Human supplementary motor area is active in preparation for both voluntary muscle relaxation and contraction
T2 - Subdural recording of Bereitschaftspotential
AU - Yazawa, Shogo
AU - Ikeda, Akio
AU - Kunieda, Takeharu
AU - Mima, Tatsuya
AU - Nagamine, Takashi
AU - Ohara, Shinji
AU - Terada, Kiyohito
AU - Taki, Waro
AU - Kimura, Jun
AU - Shibasaki, Hiroshi
PY - 1998/3/20
Y1 - 1998/3/20
N2 - Bereitschaftspotentials (BPs) preceding muscle relaxation and contraction were compared by using subdural electrodes which were implanted onto the right medial frontal surface in two patients with supplementary motor area (SMA) seizure. The applied movement paradigm (muscle relaxation and contraction tasks) was completely the same as employed in our previous study [Terada, K., Ikeda, A., Nagamine, T. and Shibasaki, H., Electroenceph. clin. Neurophysiol., 95 (1995) 335-345]. In both patients, either negative or positive BPs were observed in the SMA-proper and supplementary negative motor area (SNMA) starting at 1.2-1.8 prior to both movements. In one patient, BP was more widespread in the relaxation task whereas more restricted to the hand area in the contraction task. In the other patient, the BPs were observed in the cortical area rostral to SNMA (pre-SMA), in addition to the SMA-proper, in both tasks. It is concluded that SMA-proper and SNMA, and probably pre-SMA as well, in humans are similarly active in preparation for both voluntary muscle contraction and relaxation.
AB - Bereitschaftspotentials (BPs) preceding muscle relaxation and contraction were compared by using subdural electrodes which were implanted onto the right medial frontal surface in two patients with supplementary motor area (SMA) seizure. The applied movement paradigm (muscle relaxation and contraction tasks) was completely the same as employed in our previous study [Terada, K., Ikeda, A., Nagamine, T. and Shibasaki, H., Electroenceph. clin. Neurophysiol., 95 (1995) 335-345]. In both patients, either negative or positive BPs were observed in the SMA-proper and supplementary negative motor area (SNMA) starting at 1.2-1.8 prior to both movements. In one patient, BP was more widespread in the relaxation task whereas more restricted to the hand area in the contraction task. In the other patient, the BPs were observed in the cortical area rostral to SNMA (pre-SMA), in addition to the SMA-proper, in both tasks. It is concluded that SMA-proper and SNMA, and probably pre-SMA as well, in humans are similarly active in preparation for both voluntary muscle contraction and relaxation.
KW - Bereitschaftspotential
KW - Central motor control
KW - Negative motor phenomenon
KW - Pre-supplementary motor area
KW - Supplementary motor area
KW - Voluntary muscle relaxation
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U2 - 10.1016/S0304-3940(98)00149-9
DO - 10.1016/S0304-3940(98)00149-9
M3 - Article
C2 - 9593510
AN - SCOPUS:0032549814
SN - 0304-3940
VL - 244
SP - 145
EP - 148
JO - Neuroscience Letters
JF - Neuroscience Letters
IS - 3
ER -