Human-rodent contact and infection with lymphocytic choriomeningitis and Seoul viruses in an inner-city population

J. E. Childs, G. E. Glass, T. G. Ksiazek, C. A. Rossi, J. G B Oro, J. W. Leduc

Research output: Contribution to journalArticle

Abstract

We collected 1180 sera and 1363 questionnaires with information on demography, rodent exposure, and history of travel from persons visiting a sexually transmitted disease (STD) clinic in Baltimore between 1986-1988. Serological tests for two rodent-borne viruses detected antibodies to lymphocytic choriomeningitis virus (LCMV) in 54 individuals (4.70%; n=1149) and antibodies to Seoul virus (SEOV) in three persons (0.25%; n=1180). Antibody prevalence to LCMV increased with age, but there were no racial or sexual differences. Neutralization tests and questionnaire responses implicated a domestic, rat-borne hantavirus as the source of SEOV antibody. Self-reported human-rodent contact indicated more exposure to house mice than rats within residences, although rats were more commonly sighted on streets. Infections with rodent-borne viruses were rare compared to the high rates of reported contact.

Original languageEnglish (US)
Pages (from-to)117-121
Number of pages5
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume44
Issue number2
StatePublished - 1991

Fingerprint

Seoul virus
Lymphocytic choriomeningitis virus
Rodentia
Antibodies
Infection
Population
Hantavirus
Viruses
Neutralization Tests
Baltimore
Serologic Tests
Sexually Transmitted Diseases
Demography
Serum

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

Cite this

Childs, J. E., Glass, G. E., Ksiazek, T. G., Rossi, C. A., Oro, J. G. B., & Leduc, J. W. (1991). Human-rodent contact and infection with lymphocytic choriomeningitis and Seoul viruses in an inner-city population. American Journal of Tropical Medicine and Hygiene, 44(2), 117-121.

Human-rodent contact and infection with lymphocytic choriomeningitis and Seoul viruses in an inner-city population. / Childs, J. E.; Glass, G. E.; Ksiazek, T. G.; Rossi, C. A.; Oro, J. G B; Leduc, J. W.

In: American Journal of Tropical Medicine and Hygiene, Vol. 44, No. 2, 1991, p. 117-121.

Research output: Contribution to journalArticle

Childs, J. E. ; Glass, G. E. ; Ksiazek, T. G. ; Rossi, C. A. ; Oro, J. G B ; Leduc, J. W. / Human-rodent contact and infection with lymphocytic choriomeningitis and Seoul viruses in an inner-city population. In: American Journal of Tropical Medicine and Hygiene. 1991 ; Vol. 44, No. 2. pp. 117-121.
@article{d6865a6e36ea492b85ae78761034f48f,
title = "Human-rodent contact and infection with lymphocytic choriomeningitis and Seoul viruses in an inner-city population",
abstract = "We collected 1180 sera and 1363 questionnaires with information on demography, rodent exposure, and history of travel from persons visiting a sexually transmitted disease (STD) clinic in Baltimore between 1986-1988. Serological tests for two rodent-borne viruses detected antibodies to lymphocytic choriomeningitis virus (LCMV) in 54 individuals (4.70{\%}; n=1149) and antibodies to Seoul virus (SEOV) in three persons (0.25{\%}; n=1180). Antibody prevalence to LCMV increased with age, but there were no racial or sexual differences. Neutralization tests and questionnaire responses implicated a domestic, rat-borne hantavirus as the source of SEOV antibody. Self-reported human-rodent contact indicated more exposure to house mice than rats within residences, although rats were more commonly sighted on streets. Infections with rodent-borne viruses were rare compared to the high rates of reported contact.",
author = "Childs, {J. E.} and Glass, {G. E.} and Ksiazek, {T. G.} and Rossi, {C. A.} and Oro, {J. G B} and Leduc, {J. W.}",
year = "1991",
language = "English (US)",
volume = "44",
pages = "117--121",
journal = "American Journal of Tropical Medicine and Hygiene",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "2",

}

TY - JOUR

T1 - Human-rodent contact and infection with lymphocytic choriomeningitis and Seoul viruses in an inner-city population

AU - Childs, J. E.

AU - Glass, G. E.

AU - Ksiazek, T. G.

AU - Rossi, C. A.

AU - Oro, J. G B

AU - Leduc, J. W.

PY - 1991

Y1 - 1991

N2 - We collected 1180 sera and 1363 questionnaires with information on demography, rodent exposure, and history of travel from persons visiting a sexually transmitted disease (STD) clinic in Baltimore between 1986-1988. Serological tests for two rodent-borne viruses detected antibodies to lymphocytic choriomeningitis virus (LCMV) in 54 individuals (4.70%; n=1149) and antibodies to Seoul virus (SEOV) in three persons (0.25%; n=1180). Antibody prevalence to LCMV increased with age, but there were no racial or sexual differences. Neutralization tests and questionnaire responses implicated a domestic, rat-borne hantavirus as the source of SEOV antibody. Self-reported human-rodent contact indicated more exposure to house mice than rats within residences, although rats were more commonly sighted on streets. Infections with rodent-borne viruses were rare compared to the high rates of reported contact.

AB - We collected 1180 sera and 1363 questionnaires with information on demography, rodent exposure, and history of travel from persons visiting a sexually transmitted disease (STD) clinic in Baltimore between 1986-1988. Serological tests for two rodent-borne viruses detected antibodies to lymphocytic choriomeningitis virus (LCMV) in 54 individuals (4.70%; n=1149) and antibodies to Seoul virus (SEOV) in three persons (0.25%; n=1180). Antibody prevalence to LCMV increased with age, but there were no racial or sexual differences. Neutralization tests and questionnaire responses implicated a domestic, rat-borne hantavirus as the source of SEOV antibody. Self-reported human-rodent contact indicated more exposure to house mice than rats within residences, although rats were more commonly sighted on streets. Infections with rodent-borne viruses were rare compared to the high rates of reported contact.

UR - http://www.scopus.com/inward/record.url?scp=0025730463&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025730463&partnerID=8YFLogxK

M3 - Article

VL - 44

SP - 117

EP - 121

JO - American Journal of Tropical Medicine and Hygiene

JF - American Journal of Tropical Medicine and Hygiene

SN - 0002-9637

IS - 2

ER -