TY - JOUR
T1 - Human papillomavirus vaccine update
AU - Ames, Alisa
AU - Gravitt, Patti
PY - 2007/3
Y1 - 2007/3
N2 - With the approval of Gardasil® (Merck and Co., Inc., Whitehouse Station, NJ) in June of 2006 and the pending approval of Cervarix® (GlaxoSmithKline, London, UK), two prophylactic human papilomavirus (HPV) vaccines will be available for clinical use. Randomized controlled trials have shown that both vaccines are safe and highly effective in preventing persistent infection and lesions caused by HPV 16 and 18 - the types responsible for 70% of cervical cancers worldwide. Determining an effective vaccination strategy is now the most pressing issue facing clinicians, parents, public health officials, and policy makers. We discuss the appropriate age of vaccination, vaccine acceptance, implementation strategies in low resource settings, and the future of screening.
AB - With the approval of Gardasil® (Merck and Co., Inc., Whitehouse Station, NJ) in June of 2006 and the pending approval of Cervarix® (GlaxoSmithKline, London, UK), two prophylactic human papilomavirus (HPV) vaccines will be available for clinical use. Randomized controlled trials have shown that both vaccines are safe and highly effective in preventing persistent infection and lesions caused by HPV 16 and 18 - the types responsible for 70% of cervical cancers worldwide. Determining an effective vaccination strategy is now the most pressing issue facing clinicians, parents, public health officials, and policy makers. We discuss the appropriate age of vaccination, vaccine acceptance, implementation strategies in low resource settings, and the future of screening.
UR - http://www.scopus.com/inward/record.url?scp=33947273719&partnerID=8YFLogxK
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U2 - 10.1007/s11908-007-0011-6
DO - 10.1007/s11908-007-0011-6
M3 - Review article
C2 - 17324353
AN - SCOPUS:33947273719
SN - 1523-3847
VL - 9
SP - 151
EP - 158
JO - Current Infectious Disease Reports
JF - Current Infectious Disease Reports
IS - 2
ER -