Human papillomavirus in women with vulvar intraepithelial neoplasia III

R. W. Jones, J. S. Park, M. R. McLean, K. V. Shah

Research output: Contribution to journalArticle

Abstract

Untreated cases of vulvar intraepithelial neoplasia (VIN) III may progress to invasive vulvar carcinoma. Tissues from 29 New Zealand women with VIN III were examined for the presence of human papillomavirus (HPV) types 6, 11, 16 and 18 by in situ hybridization and polymerase chain reaction. HPV 16, the only HPV type detected in the lesions, was identified in about half the cases. HPV-positive women were younger than HPV-negative women, and their lesions displayed koilocytosis more often. In four of five cases in which there was a progression to invasive cancer, HPV 16 was detected in both the VIN III and invasive cancer tissue.

Original languageEnglish (US)
Pages (from-to)1124-1126
Number of pages3
JournalJournal of Reproductive Medicine for the Obstetrician and Gynecologist
Volume35
Issue number12
StatePublished - 1990

Fingerprint

Human papillomavirus 16
Neoplasms
Human papillomavirus 11
Human papillomavirus 6
Human papillomavirus 18
New Zealand
In Situ Hybridization
Carcinoma
Polymerase Chain Reaction

ASJC Scopus subject areas

  • Obstetrics and Gynecology
  • Reproductive Medicine

Cite this

Human papillomavirus in women with vulvar intraepithelial neoplasia III. / Jones, R. W.; Park, J. S.; McLean, M. R.; Shah, K. V.

In: Journal of Reproductive Medicine for the Obstetrician and Gynecologist, Vol. 35, No. 12, 1990, p. 1124-1126.

Research output: Contribution to journalArticle

Jones, R. W. ; Park, J. S. ; McLean, M. R. ; Shah, K. V. / Human papillomavirus in women with vulvar intraepithelial neoplasia III. In: Journal of Reproductive Medicine for the Obstetrician and Gynecologist. 1990 ; Vol. 35, No. 12. pp. 1124-1126.
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