Human Immunodeficiency Virus-Associated Tuberculosis. Update on Prevention and Treatment.

Kerry L. Dierberg, Richard E. Chaisson

Research output: Contribution to journalReview articlepeer-review

Abstract

Tuberculosis (TB) is the leading cause of opportunistic infection and mortality among HIV-infected persons. Screening for symptoms of TB in people with HIV infection, use of isoniazid preventive therapy for those with latent TB infection, earlier diagnosis and treatment of active TB disease, and early initiation of antiretroviral therapy are essential for controlling the spread of TB. Treatment of HIV-related TB is complicated by overlapping drug toxicities and drug-drug interactions between antiretroviral therapy and anti-TB therapy and risk for development of immune reconstitution inflammatory disease. This review provides an overview of the prevention and treatment of TB in HIV-infected persons.

Original languageEnglish (US)
Pages (from-to)217-228
Number of pages12
JournalClinics in Chest Medicine
Volume34
Issue number2
DOIs
StatePublished - Jun 2013

Keywords

  • HIV-associated tuberculosis
  • Human immunodeficiency virus
  • Tuberculosis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

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