Human heredity and health (H3) in africa kidney disease research network: A focus on methods in sub-Saharan Africa

Charlotte Osafo, Yemi Raheem Raji, David Burke, Bamidele O. Tayo, Nicki Tiffin, Marva M. Moxey-Mims, Rebekah S. Rasooly, Paul L. Kimmel, Akinlolu Ojo, Dwomoa Adu, Rulan S. Parekh

Research output: Contribution to journalArticle

Abstract

CKD affects an estimated 14% of adults in sub-Saharan Africa, but very little research has been done on the cause, progression, and prevention of CKD there. As part of the Human Heredity and Health in Africa (H3Africa) Consortium, the H3Africa Kidney Disease Research Network was established to study prevalent forms of kidney disease in sub-Saharan Africa and increase the capacity for genetics and genomics research. The study is performing comprehensive phenotypic characterization and analyzing environmental and genetic factors from nine clinical centers in four African countries (Ghana, Nigeria, Ethiopia, and Kenya) over a 5-year period. Approximately 4000 participants with specified kidney disease diagnoses and 4000 control participants will be enrolled in the four African countries. In addition, approximately 50 families with hereditary glomerular disease will be enrolled. The study includes both pediatric and adult participants age

Original languageEnglish (US)
Pages (from-to)2279-2287
Number of pages9
JournalClinical Journal of the American Society of Nephrology
Volume10
Issue number12
DOIs
StatePublished - Dec 7 2015
Externally publishedYes

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ASJC Scopus subject areas

  • Nephrology
  • Transplantation
  • Epidemiology
  • Critical Care and Intensive Care Medicine

Cite this

Osafo, C., Raji, Y. R., Burke, D., Tayo, B. O., Tiffin, N., Moxey-Mims, M. M., Rasooly, R. S., Kimmel, P. L., Ojo, A., Adu, D., & Parekh, R. S. (2015). Human heredity and health (H3) in africa kidney disease research network: A focus on methods in sub-Saharan Africa. Clinical Journal of the American Society of Nephrology, 10(12), 2279-2287. https://doi.org/10.2215/CJN.11951214