Human Granulocytic Anaplasmosis

Johan S. Bakken, J. Stephen Dumler

Research output: Contribution to journalReview articlepeer-review

Abstract

Human granulocytic anaplasmosis, a deer tick-transmitted rickettsial infection caused by Anaplasma phagocytophilum, is a common cause of undifferentiated fever in the northeast and upper Midwest United States. Patients are often initially diagnosed with a mild viral infection, and illness readily resolves in most cases. However, as many as 3% develop life-threatening complications and nearly 1% die from the infection. Although coinfections with Borrelia burgdorferi and Babesia microti occur, there is little evidence to suggest synergism of disease or a role for A phagocytophilum in chronic illness. No vaccine is available.

Original languageEnglish (US)
Pages (from-to)341-355
Number of pages15
JournalInfectious disease clinics of North America
Volume29
Issue number2
DOIs
StatePublished - Jun 1 2015

Keywords

  • Anaplasmosis
  • Diagnosis
  • Granulocytic
  • Human
  • Management

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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