Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR

David J. Vandenbergh, Antonio M. Persico, Anita L. Hawkins, Constance A. Griffin, Xiang Li, Ethylin Wang Jabs, George R. Uhl

Research output: Contribution to journalArticle

Abstract

The human dopamine transporter (DAT1) gene is localized to chromosome 5p15.3 by in situ hybridization and PCR amplification of rodent somatic cell hybrid DNA. Analysis of a 40-bp repeat in the 3′ untranslated region of the message revealed variable numbers of the repeat ranging from 3 to 11 copies. These results will aid in the investigation of a role for this gene in genetic disorders of the dopaminergic system in humans.

Original languageEnglish (US)
Pages (from-to)1104-1106
Number of pages3
JournalGenomics
Volume14
Issue number4
DOIs
StatePublished - 1992

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Dopamine Plasma Membrane Transport Proteins
Chromosomes
Inborn Genetic Diseases
Hybrid Cells
3' Untranslated Regions
Genes
In Situ Hybridization
Rodentia
Polymerase Chain Reaction
DNA

ASJC Scopus subject areas

  • Genetics

Cite this

Vandenbergh, D. J., Persico, A. M., Hawkins, A. L., Griffin, C. A., Li, X., Jabs, E. W., & Uhl, G. R. (1992). Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR. Genomics, 14(4), 1104-1106. https://doi.org/10.1016/S0888-7543(05)80138-7

Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR. / Vandenbergh, David J.; Persico, Antonio M.; Hawkins, Anita L.; Griffin, Constance A.; Li, Xiang; Jabs, Ethylin Wang; Uhl, George R.

In: Genomics, Vol. 14, No. 4, 1992, p. 1104-1106.

Research output: Contribution to journalArticle

Vandenbergh, DJ, Persico, AM, Hawkins, AL, Griffin, CA, Li, X, Jabs, EW & Uhl, GR 1992, 'Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR', Genomics, vol. 14, no. 4, pp. 1104-1106. https://doi.org/10.1016/S0888-7543(05)80138-7
Vandenbergh DJ, Persico AM, Hawkins AL, Griffin CA, Li X, Jabs EW et al. Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR. Genomics. 1992;14(4):1104-1106. https://doi.org/10.1016/S0888-7543(05)80138-7
Vandenbergh, David J. ; Persico, Antonio M. ; Hawkins, Anita L. ; Griffin, Constance A. ; Li, Xiang ; Jabs, Ethylin Wang ; Uhl, George R. / Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR. In: Genomics. 1992 ; Vol. 14, No. 4. pp. 1104-1106.
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