Human cellular immune response to measles virus polypeptides

J. W. Rose, W. J. Bellini, D. E. McFarlin, H. F. McFarland

Research output: Contribution to journalArticlepeer-review

Abstract

Measles virus polypeptides were separated by polyacrylamide gel electrophoresis and electroeluted from gel sections. The antigenicity of the polypeptides was determined by enzyme-linked immunosorbent assays. The ability of these measles virus antigens to stimulate lymphoproliferation was measured in both high- and low-responder individuals. In contrast to the low-responder lymphocytes which did not proliferate when stimulated with measles virus antigens, the high-responder lymphocytes proliferated when challenged with hemagglutinin, nucleocapsid-associated phosphoprotein, nucleocapsid protein, matrix protein, and fusion protein.

Original languageEnglish (US)
Pages (from-to)988-991
Number of pages4
JournalJournal of Virology
Volume49
Issue number3
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Immunology

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