HTLV-III Antibody in East Africa

Donald N. Forthal, Andrew Friede, Justin C. Mason, Robert M.c.Schuster Bruce, Berge S. Azadian, Robert A. Wall, Joan Kreiss, Davy Koech, Francis Plummer, King K. Holmes, Marilyn Lightfoote, Peter Piot, Allan R. Ronald, J. O. Ndinya-Achola, Lourdes J. D'costa, Pacita Roberts, Elizabeth Ngugi, Thomas C. Quinn

Research output: Contribution to journalLetter


To the Editor: In their article about AIDS virus infection in Nairobi prostitutes, (Feb. 13 issue),1 Kreiss et al. concluded that their data support the hypothesis of transcontinental spread of AIDS from central Africa to Kenya. We believe that the data do not justify this conclusion. Kreiss et al. reported an odds ratio as the estimator of the relative risk of having HTLV-III/LAV antibody in association with sexual exposure to men from various African countries and from North America and Europe. The odds ratio is a good estimator of relative risk only when the disease is rare in the population.

Original languageEnglish (US)
Pages (from-to)259-260
Number of pages2
JournalNew England Journal of Medicine
Issue number4
StatePublished - Jul 24 1986
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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    Forthal, D. N., Friede, A., Mason, J. C., Bruce, R. M. C. S., Azadian, B. S., Wall, R. A., Kreiss, J., Koech, D., Plummer, F., Holmes, K. K., Lightfoote, M., Piot, P., Ronald, A. R., Ndinya-Achola, J. O., D'costa, L. J., Roberts, P., Ngugi, E., & Quinn, T. C. (1986). HTLV-III Antibody in East Africa. New England Journal of Medicine, 315(4), 259-260.