HSP90 protects the human T-cell leukemia virus type 1 (HTLV-1) tax oncoprotein from proteasomal degradation to support NF-κB activation and HTLV-1 replication

Agriculture & Biology

• Primate T-lymphotropic viruses 100%
• oncogene proteins 84%
• heat-shock protein 90 82%
• taxes 73%
• degradation 35%
• T-lymphocytes 24%
• leukemia 13%
• proteins 11%
• nuclear matrix 9%
• terminal repeat sequences 7%
• confocal microscopy 7%
• virus replication 7%
• cell death 6%
• cell proliferation 5%
• mass spectrometry 5%
• therapeutics 5%
• cell lines 4%
• cells 4%
• genome 3%
• assays 3%

Medicine & Life Sciences

• Deltaretrovirus 82%
• HSP90 Heat-Shock Proteins 78%
• Oncogene Proteins 66%
• Virus Replication 59%
• tax Gene Products 30%
• 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin 23%
• Tropical Spastic Paraparesis 19%
• Adult T Cell Leukemia Lymphoma 17%
• Spinal Cord Diseases 14%
• Tandem Affinity Purification 10%
• Nuclear Matrix 8%
• Human T-lymphotropic virus 1 8%
• T-Lymphocytes 8%
• Terminal Repeat Sequences 7%
• Confocal Microscopy 6%
• Mass Spectrometry 5%
• Cell Death 4%
• Proteins 4%
• Genome 4%
• Cell Proliferation 4%
• Therapeutics 3%