HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging

Jing Huang; Jin Xie; Kai Chen; Lihong Bu; Seulki Lee; Zhen Cheng; Xingguo Li; Xiaoyuan Chen

doi:10.1039/c0cc01041c

HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging

Jing Huang, Jin Xie, Kai Chen, Lihong Bu, Seulki Lee, Zhen Cheng, Xingguo Li, Xiaoyuan Chen

Research output: Contribution to journal › Article › peer-review

115 Scopus citations

Abstract

We report in this Communication a facile, two-step surface modification strategy to achieve manganese oxide nanoparticles with prominent MRI T1 contrast. In a U87MG glioblastoma xenograft model, we confirmed that the particles can accumulate efficiently in tumor area to induce effective T1 signal alteration.

Original language	English (US)
Pages (from-to)	6684-6686
Number of pages	3
Journal	Chemical Communications
Volume	46
Issue number	36
DOIs	https://doi.org/10.1039/c0cc01041c
State	Published - Sep 28 2010
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c0cc01041c

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title = "HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging",

abstract = "We report in this Communication a facile, two-step surface modification strategy to achieve manganese oxide nanoparticles with prominent MRI T1 contrast. In a U87MG glioblastoma xenograft model, we confirmed that the particles can accumulate efficiently in tumor area to induce effective T1 signal alteration.",

author = "Jing Huang and Jin Xie and Kai Chen and Lihong Bu and Seulki Lee and Zhen Cheng and Xingguo Li and Xiaoyuan Chen",

year = "2010",

month = sep,

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doi = "10.1039/c0cc01041c",

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T1 - HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging

AU - Huang, Jing

AU - Xie, Jin

AU - Chen, Kai

AU - Bu, Lihong

AU - Lee, Seulki

AU - Cheng, Zhen

AU - Li, Xingguo

AU - Chen, Xiaoyuan

PY - 2010/9/28

Y1 - 2010/9/28

N2 - We report in this Communication a facile, two-step surface modification strategy to achieve manganese oxide nanoparticles with prominent MRI T1 contrast. In a U87MG glioblastoma xenograft model, we confirmed that the particles can accumulate efficiently in tumor area to induce effective T1 signal alteration.

AB - We report in this Communication a facile, two-step surface modification strategy to achieve manganese oxide nanoparticles with prominent MRI T1 contrast. In a U87MG glioblastoma xenograft model, we confirmed that the particles can accumulate efficiently in tumor area to induce effective T1 signal alteration.

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U2 - 10.1039/c0cc01041c

DO - 10.1039/c0cc01041c

M3 - Article

C2 - 20730157

AN - SCOPUS:77956337298

SN - 1359-7345

VL - 46

SP - 6684

EP - 6686

JO - Chemical Communications

JF - Chemical Communications

IS - 36

ER -

HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging

Abstract

ASJC Scopus subject areas

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