HSA coated MnO nanoparticles with prominent MRI contrast for tumor imaging

Jing Huang, Jin Xie, Kai Chen, Lihong Bu, Seulki Lee, Zhen Cheng, Xingguo Li, Xiaoyuan Chen

Research output: Contribution to journalArticlepeer-review

Abstract

We report in this Communication a facile, two-step surface modification strategy to achieve manganese oxide nanoparticles with prominent MRI T1 contrast. In a U87MG glioblastoma xenograft model, we confirmed that the particles can accumulate efficiently in tumor area to induce effective T1 signal alteration.

Original languageEnglish (US)
Pages (from-to)6684-6686
Number of pages3
JournalChemical Communications
Volume46
Issue number36
DOIs
StatePublished - Sep 28 2010
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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