HPTN 068: A Randomized Control Trial of a Conditional Cash Transfer to Reduce HIV Infection in Young Women in South Africa—Study Design and Baseline Results

Audrey Pettifor; Catherine MacPhail; Amanda Selin; F. Xavier Gómez-Olivé; Molly Rosenberg; Ryan G. Wagner; Wonderful Mabuza; James P. Hughes; Chirayath Suchindran; Estelle Piwowar-Manning; Jing Wang; Rhian Twine; Tamu Daniel; Philip Andrew; Oliver Laeyendecker; Yaw Agyei; Stephen Tollman; Kathleen Kahn; HPTN 068 protocol team The HPTN 068 protocol team

doi:10.1007/s10461-015-1270-0

HPTN 068: A Randomized Control Trial of a Conditional Cash Transfer to Reduce HIV Infection in Young Women in South Africa—Study Design and Baseline Results

Audrey Pettifor, Catherine MacPhail, Amanda Selin, F. Xavier Gómez-Olivé, Molly Rosenberg, Ryan G. Wagner, Wonderful Mabuza, James P. Hughes, Chirayath Suchindran, Estelle Piwowar-Manning, Jing Wang, Rhian Twine, Tamu Daniel, Philip Andrew, Oliver Laeyendecker, Yaw Agyei, Stephen Tollman, Kathleen Kahn, HPTN 068 protocol team The HPTN 068 protocol team

School of Medicine

Research output: Contribution to journal › Article › peer-review

57 Scopus citations

Abstract

Young women in South Africa are at high risk for HIV infection. Cash transfers offer promise to reduce HIV risk. We present the design and baseline results from HPTN 068, a phase III, individually randomized trial to assess the effect of a conditional cash transfer on HIV acquisition among South African young women. A total of 2533 young women were randomized to receive a monthly cash transfer conditional on school attendance or to a control group. A number of individual-, partner-, household- and school-level factors were associated with HIV and HSV-2 infection. After adjusting for age, all levels were associated with an increased odds of HIV infection with partner-level factors conveying the strongest association (aOR 3.05 95 % CI 1.84–5.06). Interventions like cash transfers that address structural factors such as schooling and poverty have the potential to reduce HIV risk in young women in South Africa.

Original language	English (US)
Pages (from-to)	1863-1882
Number of pages	20
Journal	AIDS and behavior
Volume	20
Issue number	9
DOIs	https://doi.org/10.1007/s10461-015-1270-0
State	Published - Sep 1 2016

Keywords

Adolescents
Cash transfers
Education
HIV
HIV prevention
South Africa
Young women

ASJC Scopus subject areas

Social Psychology
Public Health, Environmental and Occupational Health
Infectious Diseases

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10.1007/s10461-015-1270-0

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Pettifor, A., MacPhail, C., Selin, A., Gómez-Olivé, F. X., Rosenberg, M., Wagner, R. G., Mabuza, W., Hughes, J. P., Suchindran, C., Piwowar-Manning, E., Wang, J., Twine, R., Daniel, T., Andrew, P., Laeyendecker, O., Agyei, Y., Tollman, S., Kahn, K., & The HPTN 068 protocol team, HPTN. . P. T. (2016). HPTN 068: A Randomized Control Trial of a Conditional Cash Transfer to Reduce HIV Infection in Young Women in South Africa—Study Design and Baseline Results. AIDS and behavior, 20(9), 1863-1882. https://doi.org/10.1007/s10461-015-1270-0

Pettifor, A, MacPhail, C, Selin, A, Gómez-Olivé, FX, Rosenberg, M, Wagner, RG, Mabuza, W, Hughes, JP, Suchindran, C, Piwowar-Manning, E, Wang, J, Twine, R, Daniel, T, Andrew, P, Laeyendecker, O, Agyei, Y, Tollman, S, Kahn, K & The HPTN 068 protocol team, HPTNPT 2016, 'HPTN 068: A Randomized Control Trial of a Conditional Cash Transfer to Reduce HIV Infection in Young Women in South Africa—Study Design and Baseline Results', AIDS and behavior, vol. 20, no. 9, pp. 1863-1882. https://doi.org/10.1007/s10461-015-1270-0

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HPTN 068: A Randomized Control Trial of a Conditional Cash Transfer to Reduce HIV Infection in Young Women in South Africa—Study Design and Baseline Results

Abstract

Keywords

ASJC Scopus subject areas

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