hPDI: A database of experimental human protein-DNA interactions

Zhi Xie; Shaohui Hu; Seth Blackshaw; Heng Zhu; Jiang Qian

doi:10.1093/bioinformatics/btp631

hPDI: A database of experimental human protein-DNA interactions

Zhi Xie, Shaohui Hu, Seth Blackshaw, Heng Zhu, Jiang Qian

School of Medicine

Research output: Contribution to journal › Article › peer-review

59 Scopus citations

Abstract

Summary: The human protein DNA Interactome (hPDI) database holds experimental protein-DNA interaction data for humans identified by protein microarray assays. The unique characteristics of hPDI are that it contains consensus DNA-binding sequences not only for nearly 500 human transcription factors but also for >500 unconventional DNA-binding proteins, which are completely uncharacterized previously. Users can browse, search and download a subset or the entire data via a web interface. This database is freely accessible for any academic purposes.

Original language	English (US)
Article number	btp631
Pages (from-to)	287-289
Number of pages	3
Journal	Bioinformatics
Volume	26
Issue number	2
DOIs	https://doi.org/10.1093/bioinformatics/btp631
State	Published - Jan 2010

ASJC Scopus subject areas

Statistics and Probability
Biochemistry
Molecular Biology
Computer Science Applications
Computational Theory and Mathematics
Computational Mathematics

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title = "hPDI: A database of experimental human protein-DNA interactions",

abstract = "Summary: The human protein DNA Interactome (hPDI) database holds experimental protein-DNA interaction data for humans identified by protein microarray assays. The unique characteristics of hPDI are that it contains consensus DNA-binding sequences not only for nearly 500 human transcription factors but also for >500 unconventional DNA-binding proteins, which are completely uncharacterized previously. Users can browse, search and download a subset or the entire data via a web interface. This database is freely accessible for any academic purposes.",

author = "Zhi Xie and Shaohui Hu and Seth Blackshaw and Heng Zhu and Jiang Qian",

note = "Funding Information: Funding: National Institutes of Health; W. M. Keck Foundation Distinguished Young Investigator in Medical Research Award; Ruth and Milton Steinbach Fund; generous gift from Mr and Mrs Robert and Clarice Smith.",

year = "2010",

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doi = "10.1093/bioinformatics/btp631",

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AU - Hu, Shaohui

AU - Blackshaw, Seth

AU - Zhu, Heng

AU - Qian, Jiang

N1 - Funding Information: Funding: National Institutes of Health; W. M. Keck Foundation Distinguished Young Investigator in Medical Research Award; Ruth and Milton Steinbach Fund; generous gift from Mr and Mrs Robert and Clarice Smith.

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N2 - Summary: The human protein DNA Interactome (hPDI) database holds experimental protein-DNA interaction data for humans identified by protein microarray assays. The unique characteristics of hPDI are that it contains consensus DNA-binding sequences not only for nearly 500 human transcription factors but also for >500 unconventional DNA-binding proteins, which are completely uncharacterized previously. Users can browse, search and download a subset or the entire data via a web interface. This database is freely accessible for any academic purposes.

AB - Summary: The human protein DNA Interactome (hPDI) database holds experimental protein-DNA interaction data for humans identified by protein microarray assays. The unique characteristics of hPDI are that it contains consensus DNA-binding sequences not only for nearly 500 human transcription factors but also for >500 unconventional DNA-binding proteins, which are completely uncharacterized previously. Users can browse, search and download a subset or the entire data via a web interface. This database is freely accessible for any academic purposes.

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hPDI: A database of experimental human protein-DNA interactions

Abstract

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