How long should we fear? Long-term risk of venous thromboembolism in patients with traumatic brain injury

Olubode A. Olufajo, Brain K. Yorkgitis, Zara Cooper, Arturo Rios-Diaz, David Metcalfe, Joaquim M. Havens, Edward Kelly, Adil H. Haider, Jonathan D. Gates, Ali Salim

Research output: Contribution to journalArticlepeer-review

Abstract

BACKGROUND: Although patients with traumatic brain injury (TBI) are known to be at high risk for venous thromboembolism (VTE), it is not clear how long this risk persists after injury. We aimed to determine the risk of VTE in TBI patients during one year following injury and to identify associated factors. METHODS: Patients 18 years and older with ICD-9-CM diagnoses of isolated TBI (Head Abbreviated Injury Scale (AIS) ≥3 and AIS 64 years vs. 18 – 44 years [2.62 (1.80–3.81)], having an operation during the index admission [1.65 (1.36–2.01)], and hospital length of stay >7 days vs. ≤3 days [1.64 (1.27–2.11)]. CONCLUSION: The risk of VTE persists long after discharge in a significant proportion of patients with TBI. Demographic and admission characteristics of patients play significant roles in the risk of VTE after discharge. These results highlight the need for sustained surveillance and preventive measures among TBI patients at increased risk for long-term VTE. LEVEL OF EVIDENCE: Level III, Epidemiologic

Original languageEnglish (US)
JournalThe journal of trauma and acute care surgery
DOIs
StateAccepted/In press - Mar 25 2016
Externally publishedYes

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine
  • Surgery

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