How effective were lifestyle interventions in real-world settings that were modeled on the diabetes prevention program?

Mohammed K. Ali, Justin Echouffo-Tcheugui, David F. Williamson

Research output: Contribution to journalArticle

Abstract

We conducted a systematic review and meta-analysis of twentyeight US-based studies applying the findings of the Diabetes Prevention Program, a clinical trial that tested the effects of a lifestyle intervention for people at high risk for diabetes, in real-world settings. The average weight change at twelve months after the intervention was a loss of about 4 percent from participants' baseline weight. Change in weight was similar regardless of whether the intervention was delivered by clinically trained professionals or lay educators. Additional analyses limited to seventeen studies with a nine-month or greater follow-up assessment showed similar weight change. With every additional lifestyle session attended, weight loss increased by 0.26 percentage point. We conclude that costs associated with diabetes prevention can be lowered without sacrificing effectiveness, using nonmedical personnel and motivating higher attendance at program sessions.

Original languageEnglish (US)
Pages (from-to)67-75
Number of pages9
JournalHealth Affairs
Volume31
Issue number1
DOIs
StatePublished - Jan 1 2012
Externally publishedYes

ASJC Scopus subject areas

  • Health Policy

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