How can drug discovery for psychiatric disorders be improved?

Yves Agid, György Buzsáki, David M. Diamond, Richard Frackowiak, Jay Giedd, Jean Antoine Girault, Anthony Grace, Jeremy J. Lambert, Husseini Manji, Helen Mayberg, Maurizio Popoli, Alain Prochiantz, Gal Richter-Levin, Peter Somogyi, Michael Spedding, Per Svenningsson, Daniel Weinberger