Housing conditions influence motor functions and exploratory behavior following focal damage of the rat brain

Elzbieta Gornicka-Pawlak, Anna Jablonska, Andrzej Chylinski, Krystyna Domańska-Janik

Research output: Contribution to journalArticle

Abstract

The present study investigated influence of housing conditions on motor functions recovery and exploratory behavior following ouabain focal brain lesion in the rat. During 30 days post-surgery period rats were housed individually in standard cages (IS) or in groups in enriched environment (EE) and behaviorally tested. The EE lesioned rats showed enhanced recovery from motor impairments in walking beam task, comparing with IS animals. Contrarily, in the open field IS rats (both lesioned and control) traveled a longer distance, showed less habituation and spent less time resting at the home base than the EE animals. Unlike the EE lesioned animals, the lesioned IS rats, presented a tendency to hyperactivity in post-injury period. Turning tendency was significantly affected by unilateral brain lesion only in the EE rats. We can conclude that housing conditions distinctly affected the rat's behavior in classical laboratory tests.

Original languageEnglish (US)
Pages (from-to)62-72
Number of pages11
JournalActa Neurobiologiae Experimentalis
Volume69
Issue number1
StatePublished - Dec 1 2009
Externally publishedYes

Fingerprint

Exploratory Behavior
Brain
Recovery of Function
Ouabain
Ambulatory Surgical Procedures
Walking
Wounds and Injuries

Keywords

  • Exploratory behavior
  • Focal brain damage
  • Functional recovery
  • Video-tracking system

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Housing conditions influence motor functions and exploratory behavior following focal damage of the rat brain. / Gornicka-Pawlak, Elzbieta; Jablonska, Anna; Chylinski, Andrzej; Domańska-Janik, Krystyna.

In: Acta Neurobiologiae Experimentalis, Vol. 69, No. 1, 01.12.2009, p. 62-72.

Research output: Contribution to journalArticle

Gornicka-Pawlak, Elzbieta ; Jablonska, Anna ; Chylinski, Andrzej ; Domańska-Janik, Krystyna. / Housing conditions influence motor functions and exploratory behavior following focal damage of the rat brain. In: Acta Neurobiologiae Experimentalis. 2009 ; Vol. 69, No. 1. pp. 62-72.
@article{e614e1e9e3ac40b697b15f61231f1e74,
title = "Housing conditions influence motor functions and exploratory behavior following focal damage of the rat brain",
abstract = "The present study investigated influence of housing conditions on motor functions recovery and exploratory behavior following ouabain focal brain lesion in the rat. During 30 days post-surgery period rats were housed individually in standard cages (IS) or in groups in enriched environment (EE) and behaviorally tested. The EE lesioned rats showed enhanced recovery from motor impairments in walking beam task, comparing with IS animals. Contrarily, in the open field IS rats (both lesioned and control) traveled a longer distance, showed less habituation and spent less time resting at the home base than the EE animals. Unlike the EE lesioned animals, the lesioned IS rats, presented a tendency to hyperactivity in post-injury period. Turning tendency was significantly affected by unilateral brain lesion only in the EE rats. We can conclude that housing conditions distinctly affected the rat's behavior in classical laboratory tests.",
keywords = "Exploratory behavior, Focal brain damage, Functional recovery, Video-tracking system",
author = "Elzbieta Gornicka-Pawlak and Anna Jablonska and Andrzej Chylinski and Krystyna Domańska-Janik",
year = "2009",
month = "12",
day = "1",
language = "English (US)",
volume = "69",
pages = "62--72",
journal = "Acta Neurobiologiae Experimentalis",
issn = "0065-1400",
publisher = "Nencki Institute of Experimental Biology",
number = "1",

}

TY - JOUR

T1 - Housing conditions influence motor functions and exploratory behavior following focal damage of the rat brain

AU - Gornicka-Pawlak, Elzbieta

AU - Jablonska, Anna

AU - Chylinski, Andrzej

AU - Domańska-Janik, Krystyna

PY - 2009/12/1

Y1 - 2009/12/1

N2 - The present study investigated influence of housing conditions on motor functions recovery and exploratory behavior following ouabain focal brain lesion in the rat. During 30 days post-surgery period rats were housed individually in standard cages (IS) or in groups in enriched environment (EE) and behaviorally tested. The EE lesioned rats showed enhanced recovery from motor impairments in walking beam task, comparing with IS animals. Contrarily, in the open field IS rats (both lesioned and control) traveled a longer distance, showed less habituation and spent less time resting at the home base than the EE animals. Unlike the EE lesioned animals, the lesioned IS rats, presented a tendency to hyperactivity in post-injury period. Turning tendency was significantly affected by unilateral brain lesion only in the EE rats. We can conclude that housing conditions distinctly affected the rat's behavior in classical laboratory tests.

AB - The present study investigated influence of housing conditions on motor functions recovery and exploratory behavior following ouabain focal brain lesion in the rat. During 30 days post-surgery period rats were housed individually in standard cages (IS) or in groups in enriched environment (EE) and behaviorally tested. The EE lesioned rats showed enhanced recovery from motor impairments in walking beam task, comparing with IS animals. Contrarily, in the open field IS rats (both lesioned and control) traveled a longer distance, showed less habituation and spent less time resting at the home base than the EE animals. Unlike the EE lesioned animals, the lesioned IS rats, presented a tendency to hyperactivity in post-injury period. Turning tendency was significantly affected by unilateral brain lesion only in the EE rats. We can conclude that housing conditions distinctly affected the rat's behavior in classical laboratory tests.

KW - Exploratory behavior

KW - Focal brain damage

KW - Functional recovery

KW - Video-tracking system

UR - http://www.scopus.com/inward/record.url?scp=65549103306&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=65549103306&partnerID=8YFLogxK

M3 - Article

C2 - 19325642

AN - SCOPUS:65549103306

VL - 69

SP - 62

EP - 72

JO - Acta Neurobiologiae Experimentalis

JF - Acta Neurobiologiae Experimentalis

SN - 0065-1400

IS - 1

ER -