Hot beverages and oesophageal cancer in Southern Brazil: A case-control study

C. G. Victora, N. Muñoz, N. E. Day, L. B. Barcelos, D. A. Peccin, N. M. Braga

Research output: Contribution to journalArticle

Abstract

There is a cluster of high-incidence areas of oesophageal cancer in south-eastern South America, including Southern Brazil, Uruguay and parts of Argentina. The present case-control study investigated the hypothesis that this may be due to the drinking of mate, a traditional beverage drunk at a very high temperature, and also studied the role of other known risk factors such as alcohol and tobacco. Cases (171) and age- and sex-matched controls (342) were recruited from hospitals in the State of Rio Grande do Sul in Southern Brazil. The crude odds ratio for daily mate drinkers was 1.92 relative to those drinking less frequently than daily (p = 0.006). Other risk factors included the drinking of cachaca (a sugar cane spirit), smoking, rural residence, low fruit consumption and high intake of meats. After adjustment for these variables through conditional logistic regression, the odds ratio associated with daily mate drinking was reduced to 1.47 (90% CI = 0.87 - 2.50). Although the study failed to provide evidence of a strong association between mate and oesophageal cancer, the cluster of high rates could be explained by relative risks of the magnitude observed. This is due to the fact that approximately 70% of adult males and 50% of females are daily drinkers. In addition, this study revealed that alcohol, tobacco smoking and rural residence are the main risk factors for oesophageal cancer in this population and the fruit consumption confers some degree of protection.

Original languageEnglish (US)
Pages (from-to)710-716
Number of pages7
JournalInternational Journal of Cancer
Volume39
Issue number6
DOIs
StatePublished - 1987
Externally publishedYes

Fingerprint

Beverages
Esophageal Neoplasms
Drinking
Brazil
Case-Control Studies
Fruit
Smoking
Odds Ratio
Alcohols
Epidemiologic Effect Modifiers
Uruguay
Canes
State Hospitals
South America
Argentina
Meat
Tobacco
Logistic Models
Temperature
Incidence

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Victora, C. G., Muñoz, N., Day, N. E., Barcelos, L. B., Peccin, D. A., & Braga, N. M. (1987). Hot beverages and oesophageal cancer in Southern Brazil: A case-control study. International Journal of Cancer, 39(6), 710-716. https://doi.org/10.1002/ijc.2910390610

Hot beverages and oesophageal cancer in Southern Brazil : A case-control study. / Victora, C. G.; Muñoz, N.; Day, N. E.; Barcelos, L. B.; Peccin, D. A.; Braga, N. M.

In: International Journal of Cancer, Vol. 39, No. 6, 1987, p. 710-716.

Research output: Contribution to journalArticle

Victora, CG, Muñoz, N, Day, NE, Barcelos, LB, Peccin, DA & Braga, NM 1987, 'Hot beverages and oesophageal cancer in Southern Brazil: A case-control study', International Journal of Cancer, vol. 39, no. 6, pp. 710-716. https://doi.org/10.1002/ijc.2910390610
Victora, C. G. ; Muñoz, N. ; Day, N. E. ; Barcelos, L. B. ; Peccin, D. A. ; Braga, N. M. / Hot beverages and oesophageal cancer in Southern Brazil : A case-control study. In: International Journal of Cancer. 1987 ; Vol. 39, No. 6. pp. 710-716.
@article{679ff0be8bdc4633a13cc1eb89727eda,
title = "Hot beverages and oesophageal cancer in Southern Brazil: A case-control study",
abstract = "There is a cluster of high-incidence areas of oesophageal cancer in south-eastern South America, including Southern Brazil, Uruguay and parts of Argentina. The present case-control study investigated the hypothesis that this may be due to the drinking of mate, a traditional beverage drunk at a very high temperature, and also studied the role of other known risk factors such as alcohol and tobacco. Cases (171) and age- and sex-matched controls (342) were recruited from hospitals in the State of Rio Grande do Sul in Southern Brazil. The crude odds ratio for daily mate drinkers was 1.92 relative to those drinking less frequently than daily (p = 0.006). Other risk factors included the drinking of cachaca (a sugar cane spirit), smoking, rural residence, low fruit consumption and high intake of meats. After adjustment for these variables through conditional logistic regression, the odds ratio associated with daily mate drinking was reduced to 1.47 (90{\%} CI = 0.87 - 2.50). Although the study failed to provide evidence of a strong association between mate and oesophageal cancer, the cluster of high rates could be explained by relative risks of the magnitude observed. This is due to the fact that approximately 70{\%} of adult males and 50{\%} of females are daily drinkers. In addition, this study revealed that alcohol, tobacco smoking and rural residence are the main risk factors for oesophageal cancer in this population and the fruit consumption confers some degree of protection.",
author = "Victora, {C. G.} and N. Mu{\~n}oz and Day, {N. E.} and Barcelos, {L. B.} and Peccin, {D. A.} and Braga, {N. M.}",
year = "1987",
doi = "10.1002/ijc.2910390610",
language = "English (US)",
volume = "39",
pages = "710--716",
journal = "International Journal of Cancer",
issn = "0020-7136",
publisher = "Wiley-Liss Inc.",
number = "6",

}

TY - JOUR

T1 - Hot beverages and oesophageal cancer in Southern Brazil

T2 - A case-control study

AU - Victora, C. G.

AU - Muñoz, N.

AU - Day, N. E.

AU - Barcelos, L. B.

AU - Peccin, D. A.

AU - Braga, N. M.

PY - 1987

Y1 - 1987

N2 - There is a cluster of high-incidence areas of oesophageal cancer in south-eastern South America, including Southern Brazil, Uruguay and parts of Argentina. The present case-control study investigated the hypothesis that this may be due to the drinking of mate, a traditional beverage drunk at a very high temperature, and also studied the role of other known risk factors such as alcohol and tobacco. Cases (171) and age- and sex-matched controls (342) were recruited from hospitals in the State of Rio Grande do Sul in Southern Brazil. The crude odds ratio for daily mate drinkers was 1.92 relative to those drinking less frequently than daily (p = 0.006). Other risk factors included the drinking of cachaca (a sugar cane spirit), smoking, rural residence, low fruit consumption and high intake of meats. After adjustment for these variables through conditional logistic regression, the odds ratio associated with daily mate drinking was reduced to 1.47 (90% CI = 0.87 - 2.50). Although the study failed to provide evidence of a strong association between mate and oesophageal cancer, the cluster of high rates could be explained by relative risks of the magnitude observed. This is due to the fact that approximately 70% of adult males and 50% of females are daily drinkers. In addition, this study revealed that alcohol, tobacco smoking and rural residence are the main risk factors for oesophageal cancer in this population and the fruit consumption confers some degree of protection.

AB - There is a cluster of high-incidence areas of oesophageal cancer in south-eastern South America, including Southern Brazil, Uruguay and parts of Argentina. The present case-control study investigated the hypothesis that this may be due to the drinking of mate, a traditional beverage drunk at a very high temperature, and also studied the role of other known risk factors such as alcohol and tobacco. Cases (171) and age- and sex-matched controls (342) were recruited from hospitals in the State of Rio Grande do Sul in Southern Brazil. The crude odds ratio for daily mate drinkers was 1.92 relative to those drinking less frequently than daily (p = 0.006). Other risk factors included the drinking of cachaca (a sugar cane spirit), smoking, rural residence, low fruit consumption and high intake of meats. After adjustment for these variables through conditional logistic regression, the odds ratio associated with daily mate drinking was reduced to 1.47 (90% CI = 0.87 - 2.50). Although the study failed to provide evidence of a strong association between mate and oesophageal cancer, the cluster of high rates could be explained by relative risks of the magnitude observed. This is due to the fact that approximately 70% of adult males and 50% of females are daily drinkers. In addition, this study revealed that alcohol, tobacco smoking and rural residence are the main risk factors for oesophageal cancer in this population and the fruit consumption confers some degree of protection.

UR - http://www.scopus.com/inward/record.url?scp=0023191712&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0023191712&partnerID=8YFLogxK

U2 - 10.1002/ijc.2910390610

DO - 10.1002/ijc.2910390610

M3 - Article

C2 - 3583451

AN - SCOPUS:0023191712

VL - 39

SP - 710

EP - 716

JO - International Journal of Cancer

JF - International Journal of Cancer

SN - 0020-7136

IS - 6

ER -