Host defenses against zygomycetes

Emmanuel Roilides, Dimitrios P. Kontoyiannis, Thomas J. Walsh

Research output: Contribution to journalArticle

Abstract

Mucormycosis is a devastating disease and can occur in patients with a variety of risk factors, the most important of which are immunosuppression, anatomic barrier breakdown, iron overload, and hyperglycemia/acidosis. Similarly to what occurs with Aspergillus, the host stimulates an innate immune response against the challenging sporangiospores and invading hyphae of Zygomycetes. This article discusses the host defense to different Zygomycetes, its augmentation, and its subsequent impact on the outcome of mucormycosis.

Original languageEnglish (US)
JournalClinical Infectious Diseases
Volume54
Issue numberSUPPL. 1
DOIs
StatePublished - Feb 1 2012
Externally publishedYes

Fingerprint

Mucormycosis
Iron Overload
Hyphae
Aspergillus
Acidosis
Innate Immunity
Hyperglycemia
Immunosuppression

ASJC Scopus subject areas

  • Infectious Diseases
  • Microbiology (medical)

Cite this

Roilides, E., Kontoyiannis, D. P., & Walsh, T. J. (2012). Host defenses against zygomycetes. Clinical Infectious Diseases, 54(SUPPL. 1). https://doi.org/10.1093/cid/cir869

Host defenses against zygomycetes. / Roilides, Emmanuel; Kontoyiannis, Dimitrios P.; Walsh, Thomas J.

In: Clinical Infectious Diseases, Vol. 54, No. SUPPL. 1, 01.02.2012.

Research output: Contribution to journalArticle

Roilides, E, Kontoyiannis, DP & Walsh, TJ 2012, 'Host defenses against zygomycetes', Clinical Infectious Diseases, vol. 54, no. SUPPL. 1. https://doi.org/10.1093/cid/cir869
Roilides E, Kontoyiannis DP, Walsh TJ. Host defenses against zygomycetes. Clinical Infectious Diseases. 2012 Feb 1;54(SUPPL. 1). https://doi.org/10.1093/cid/cir869
Roilides, Emmanuel ; Kontoyiannis, Dimitrios P. ; Walsh, Thomas J. / Host defenses against zygomycetes. In: Clinical Infectious Diseases. 2012 ; Vol. 54, No. SUPPL. 1.
@article{9d7893168e524c53a109206401727fdf,
title = "Host defenses against zygomycetes",
abstract = "Mucormycosis is a devastating disease and can occur in patients with a variety of risk factors, the most important of which are immunosuppression, anatomic barrier breakdown, iron overload, and hyperglycemia/acidosis. Similarly to what occurs with Aspergillus, the host stimulates an innate immune response against the challenging sporangiospores and invading hyphae of Zygomycetes. This article discusses the host defense to different Zygomycetes, its augmentation, and its subsequent impact on the outcome of mucormycosis.",
author = "Emmanuel Roilides and Kontoyiannis, {Dimitrios P.} and Walsh, {Thomas J.}",
year = "2012",
month = "2",
day = "1",
doi = "10.1093/cid/cir869",
language = "English (US)",
volume = "54",
journal = "Clinical Infectious Diseases",
issn = "1058-4838",
publisher = "Oxford University Press",
number = "SUPPL. 1",

}

TY - JOUR

T1 - Host defenses against zygomycetes

AU - Roilides, Emmanuel

AU - Kontoyiannis, Dimitrios P.

AU - Walsh, Thomas J.

PY - 2012/2/1

Y1 - 2012/2/1

N2 - Mucormycosis is a devastating disease and can occur in patients with a variety of risk factors, the most important of which are immunosuppression, anatomic barrier breakdown, iron overload, and hyperglycemia/acidosis. Similarly to what occurs with Aspergillus, the host stimulates an innate immune response against the challenging sporangiospores and invading hyphae of Zygomycetes. This article discusses the host defense to different Zygomycetes, its augmentation, and its subsequent impact on the outcome of mucormycosis.

AB - Mucormycosis is a devastating disease and can occur in patients with a variety of risk factors, the most important of which are immunosuppression, anatomic barrier breakdown, iron overload, and hyperglycemia/acidosis. Similarly to what occurs with Aspergillus, the host stimulates an innate immune response against the challenging sporangiospores and invading hyphae of Zygomycetes. This article discusses the host defense to different Zygomycetes, its augmentation, and its subsequent impact on the outcome of mucormycosis.

UR - http://www.scopus.com/inward/record.url?scp=84855874847&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84855874847&partnerID=8YFLogxK

U2 - 10.1093/cid/cir869

DO - 10.1093/cid/cir869

M3 - Article

C2 - 22247447

AN - SCOPUS:84855874847

VL - 54

JO - Clinical Infectious Diseases

JF - Clinical Infectious Diseases

SN - 1058-4838

IS - SUPPL. 1

ER -