Host cell fate on Cryptosporidium parvum egress from MDCK cells

David A. Elliott, Douglas P. Clark

Research output: Contribution to journalArticle

Abstract

Cryptosporidium parvum is an intracellular protozoan parasite that causes a severe diarrheal illness of unclear etiology. Also unclear is the fate of the host cell upon parasite egress. We show in an MDCK cell model that the host cell is killed upon parasite egress; this death is necrotic, rather than apoptotic, in nature.

Original languageEnglish (US)
Pages (from-to)5422-5426
Number of pages5
JournalInfection and Immunity
Volume71
Issue number9
DOIs
StatePublished - Sep 1 2003

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Cryptosporidium parvum
Madin Darby Canine Kidney Cells
Parasites

ASJC Scopus subject areas

  • Immunology

Cite this

Host cell fate on Cryptosporidium parvum egress from MDCK cells. / Elliott, David A.; Clark, Douglas P.

In: Infection and Immunity, Vol. 71, No. 9, 01.09.2003, p. 5422-5426.

Research output: Contribution to journalArticle

Elliott, David A. ; Clark, Douglas P. / Host cell fate on Cryptosporidium parvum egress from MDCK cells. In: Infection and Immunity. 2003 ; Vol. 71, No. 9. pp. 5422-5426.
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