Hospital-based prevalence of malaria and dengue in febrile patients in Bangladesh

Labib I. Faruque, Rashid Uz Zaman, A. S.M. Alamgir, Emily Gurley, Rashidul Haque, Mahmudur Rahman, Stephen P. Luby

Research output: Contribution to journalArticle

Abstract

We conducted a nationwide study at six tertiary hospitals from December 2008 through November 2009 to investigate etiologies of febrile illnesses in Bangladesh. Febrile patients meeting a clinical case definition were enrolled from inpatient and outpatient medicine and pediatric units. We assessed 720 febrile patients over 12 months; 69 (9.6%) were positive for IgM antibodies against dengue virus by enzyme-linked immunosorbent assay, and four malaria patients (0.56%) were confirmed with immuno-chromatography and microscopic slide tests. We identified dengue cases throughout the year from rural (49%) and urban areas (51%). We followed-up 55 accessible dengue-infected patients two months after their initial enrollment: 45 (82%) patients had fully recovered, 9 (16%) reported ongoing jaundice, fever and/or joint pain, and one died. Dengue infection is widespread across Bangladesh, but malaria is sufficiently uncommon that it should not be assumed as the cause of fever without laboratory confirmation.

Original languageEnglish (US)
Pages (from-to)58-64
Number of pages7
JournalAmerican Journal of Tropical Medicine and Hygiene
Volume86
Issue number1
DOIs
StatePublished - Jan 1 2012
Externally publishedYes

Fingerprint

Bangladesh
Dengue
Malaria
Fever
Dengue Virus
Arthralgia
Jaundice
Tertiary Care Centers
Immunoglobulin M
Chromatography
Inpatients
Outpatients
Enzyme-Linked Immunosorbent Assay
Medicine
Pediatrics
Antibodies
Infection

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases
  • Virology

Cite this

Hospital-based prevalence of malaria and dengue in febrile patients in Bangladesh. / Faruque, Labib I.; Zaman, Rashid Uz; Alamgir, A. S.M.; Gurley, Emily; Haque, Rashidul; Rahman, Mahmudur; Luby, Stephen P.

In: American Journal of Tropical Medicine and Hygiene, Vol. 86, No. 1, 01.01.2012, p. 58-64.

Research output: Contribution to journalArticle

Faruque, Labib I. ; Zaman, Rashid Uz ; Alamgir, A. S.M. ; Gurley, Emily ; Haque, Rashidul ; Rahman, Mahmudur ; Luby, Stephen P. / Hospital-based prevalence of malaria and dengue in febrile patients in Bangladesh. In: American Journal of Tropical Medicine and Hygiene. 2012 ; Vol. 86, No. 1. pp. 58-64.
@article{bed5ac3c0971420aad92bccdfdfb5ccd,
title = "Hospital-based prevalence of malaria and dengue in febrile patients in Bangladesh",
abstract = "We conducted a nationwide study at six tertiary hospitals from December 2008 through November 2009 to investigate etiologies of febrile illnesses in Bangladesh. Febrile patients meeting a clinical case definition were enrolled from inpatient and outpatient medicine and pediatric units. We assessed 720 febrile patients over 12 months; 69 (9.6{\%}) were positive for IgM antibodies against dengue virus by enzyme-linked immunosorbent assay, and four malaria patients (0.56{\%}) were confirmed with immuno-chromatography and microscopic slide tests. We identified dengue cases throughout the year from rural (49{\%}) and urban areas (51{\%}). We followed-up 55 accessible dengue-infected patients two months after their initial enrollment: 45 (82{\%}) patients had fully recovered, 9 (16{\%}) reported ongoing jaundice, fever and/or joint pain, and one died. Dengue infection is widespread across Bangladesh, but malaria is sufficiently uncommon that it should not be assumed as the cause of fever without laboratory confirmation.",
author = "Faruque, {Labib I.} and Zaman, {Rashid Uz} and Alamgir, {A. S.M.} and Emily Gurley and Rashidul Haque and Mahmudur Rahman and Luby, {Stephen P.}",
year = "2012",
month = "1",
day = "1",
doi = "10.4269/ajtmh.2012.11-0190",
language = "English (US)",
volume = "86",
pages = "58--64",
journal = "American Journal of Tropical Medicine and Hygiene",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "1",

}

TY - JOUR

T1 - Hospital-based prevalence of malaria and dengue in febrile patients in Bangladesh

AU - Faruque, Labib I.

AU - Zaman, Rashid Uz

AU - Alamgir, A. S.M.

AU - Gurley, Emily

AU - Haque, Rashidul

AU - Rahman, Mahmudur

AU - Luby, Stephen P.

PY - 2012/1/1

Y1 - 2012/1/1

N2 - We conducted a nationwide study at six tertiary hospitals from December 2008 through November 2009 to investigate etiologies of febrile illnesses in Bangladesh. Febrile patients meeting a clinical case definition were enrolled from inpatient and outpatient medicine and pediatric units. We assessed 720 febrile patients over 12 months; 69 (9.6%) were positive for IgM antibodies against dengue virus by enzyme-linked immunosorbent assay, and four malaria patients (0.56%) were confirmed with immuno-chromatography and microscopic slide tests. We identified dengue cases throughout the year from rural (49%) and urban areas (51%). We followed-up 55 accessible dengue-infected patients two months after their initial enrollment: 45 (82%) patients had fully recovered, 9 (16%) reported ongoing jaundice, fever and/or joint pain, and one died. Dengue infection is widespread across Bangladesh, but malaria is sufficiently uncommon that it should not be assumed as the cause of fever without laboratory confirmation.

AB - We conducted a nationwide study at six tertiary hospitals from December 2008 through November 2009 to investigate etiologies of febrile illnesses in Bangladesh. Febrile patients meeting a clinical case definition were enrolled from inpatient and outpatient medicine and pediatric units. We assessed 720 febrile patients over 12 months; 69 (9.6%) were positive for IgM antibodies against dengue virus by enzyme-linked immunosorbent assay, and four malaria patients (0.56%) were confirmed with immuno-chromatography and microscopic slide tests. We identified dengue cases throughout the year from rural (49%) and urban areas (51%). We followed-up 55 accessible dengue-infected patients two months after their initial enrollment: 45 (82%) patients had fully recovered, 9 (16%) reported ongoing jaundice, fever and/or joint pain, and one died. Dengue infection is widespread across Bangladesh, but malaria is sufficiently uncommon that it should not be assumed as the cause of fever without laboratory confirmation.

UR - http://www.scopus.com/inward/record.url?scp=84855694517&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84855694517&partnerID=8YFLogxK

U2 - 10.4269/ajtmh.2012.11-0190

DO - 10.4269/ajtmh.2012.11-0190

M3 - Article

C2 - 22232452

AN - SCOPUS:84855694517

VL - 86

SP - 58

EP - 64

JO - American Journal of Tropical Medicine and Hygiene

JF - American Journal of Tropical Medicine and Hygiene

SN - 0002-9637

IS - 1

ER -