Horner syndrome after carotid sheath surgery in a pig

Anatomic study of cervical sympathetic chain

Peng Ding, Ralph P Tufano, Regina Campbell-Malone, Wallace Feng, Sang Jun Kim, Rebecca Z. German

Research output: Contribution to journalArticle

Abstract

In an experimental model, iatrogenic Horner syndrome developed after a right carotid sheath surgery in an infant pig (Sus scrofa). Horner syndrome is a classic clinical triad consisting of ipsilateral eyelid ptosis, pupil miosis, and facial anhydrosis. This syndrome results from cervical sympathetic chain (CSC) paresis and usually is acquired in humans. To determine whether the development of Horner syndrome in this situation could be attributed to pig anatomy, we compared the anatomy of the CSC in pigs and humans, by using 10 infant (age, 1 to 3 wk) pig cadavers. The CSC and cranial cervical sympathetic ganglion (CCG) were dissected bilaterally under a surgical microscope. These structures were consistently within the carotid sheaths of the pigs. In contrast, the CSC and CCG are outside the carotid sheath in humans. Awareness of the anatomic variation of the CSC and CCG within the carotid sheath in the pig and the possibility of the same variation in humans may help surgeons to identify and preserve important structures while performing cervical surgery in pigs and humans. Furthermore, this knowledge can aid in the diagnosis and prognosis of schwannoma.

Original languageEnglish (US)
Pages (from-to)453-456
Number of pages4
JournalComparative Medicine
Volume61
Issue number5
StatePublished - Oct 2011

Fingerprint

Horner Syndrome
Surgery
Swine
surgery
swine
Sympathetic Ganglia
Microscopes
Anatomy
Blepharoptosis
Anatomic Variation
Miosis
Sus scrofa
paresis
eyelids
Neurilemmoma
surgeons
Paresis
Pupil
Cadaver
microscopes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • veterinary(all)

Cite this

Ding, P., Tufano, R. P., Campbell-Malone, R., Feng, W., Kim, S. J., & German, R. Z. (2011). Horner syndrome after carotid sheath surgery in a pig: Anatomic study of cervical sympathetic chain. Comparative Medicine, 61(5), 453-456.

Horner syndrome after carotid sheath surgery in a pig : Anatomic study of cervical sympathetic chain. / Ding, Peng; Tufano, Ralph P; Campbell-Malone, Regina; Feng, Wallace; Kim, Sang Jun; German, Rebecca Z.

In: Comparative Medicine, Vol. 61, No. 5, 10.2011, p. 453-456.

Research output: Contribution to journalArticle

Ding, P, Tufano, RP, Campbell-Malone, R, Feng, W, Kim, SJ & German, RZ 2011, 'Horner syndrome after carotid sheath surgery in a pig: Anatomic study of cervical sympathetic chain', Comparative Medicine, vol. 61, no. 5, pp. 453-456.
Ding, Peng ; Tufano, Ralph P ; Campbell-Malone, Regina ; Feng, Wallace ; Kim, Sang Jun ; German, Rebecca Z. / Horner syndrome after carotid sheath surgery in a pig : Anatomic study of cervical sympathetic chain. In: Comparative Medicine. 2011 ; Vol. 61, No. 5. pp. 453-456.
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