Knowledge of neuroendocrine effects in epilepsy can aid in the management of pediatric patients with seizures. Adrenocorticotropic hormone and corticosteroids are important in infantile spasms and other types of seizures. There has been much interest in serum prolactin as an indicator of seizure activity. Hormones interact with anticonvulsant drugs and each may interfere with the actions of the other and the seizure threshold. Thyroid, anterior pituitary and sex hormones also have special importance in the modulation of seizure susceptibility. Puberty, the menstrual exacerbation of seizures and pregnancy present special problems in management.
|Original language||English (US)|
|Number of pages||8|
|Publication status||Published - 1993|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health