Hormonal therapy in breast cancer: A model disease for the personalization of cancer care

Shannon Puhalla, Saveri Bhattacharya, Nancy E. Davidson

Research output: Contribution to journalReview article

Abstract

The treatment of breast cancer is driven by subtype classification, of which the assessment of hormone receptor status is one of the important determinants of therapy. The use of hormonal therapy to treat estrogen-receptor positive breast cancer has been studied for over a century and is one of the well-described uses of personalized medicine. In this review, we will describe the classification of hormone receptor status and the various endocrine treatment strategies. Opportunities for personalization of care are illustrated.

Original languageEnglish (US)
Pages (from-to)222-236
Number of pages15
JournalMolecular oncology
Volume6
Issue number2
DOIs
StatePublished - Apr 2012

Keywords

  • Aromatase inhibitors
  • Breast cancer
  • Endocrine therapy
  • Estrogen receptor
  • Prognostic assays
  • Tamoxifen

ASJC Scopus subject areas

  • Molecular Medicine
  • Genetics
  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'Hormonal therapy in breast cancer: A model disease for the personalization of cancer care'. Together they form a unique fingerprint.

  • Cite this