TY - JOUR
T1 - HORMONAL SUPPLEMENTATION TRIGGERING CHOROIDAL NEOVASCULARIZATION in HEALTHY YOUNG FEMALES
AU - Dolz-Marco, Rosa
AU - Doménech, Nuria
AU - Diago, Teresa
AU - Montero, Javier
AU - García-Canet, Sara
AU - Cervera-Taulet, Enrique
AU - Gallego-Pinazo, Roberto
AU - Arévalo, J. Fernando
N1 - Funding Information:
R. Dolz-Marco: research grants from Alcon, Allergan, Bayer, Heidelberg Engineering, Novartis, and Thea. R. Gallego-Pinazo: research grants from Alcon, Allergan, Bayer, Heidelberg Engineering, Novartis, Thea, Consultant for Novastis, and Heidelberg Engineering. The remaining authors have no conflicting interests to disclose.
Publisher Copyright:
© Retinal Cases and Brief Reports. All rights reserved.
PY - 2019/3/1
Y1 - 2019/3/1
N2 - Purpose:To report three cases of choroidal neovascularization after hormonal treatment for ovarian stimulation during a fertility therapy.Methods:A comprehensive ophthalmic examination was performed in all cases including best-corrected visual acuity, color fundus examination, fluorescein angiography, and optical coherence tomography.Results:Three females in their thirties developed unilateral acuity vision loss and metamorphopsia. They all were undergoing hormonal supplementation for ovarian stimulation with gonadotropins at the moment of presentation. Intravitreal therapy with ranibizumab was used; all cases showed a significant functional and anatomical improvement.Discussion:Hormonal supplementation for fertility therapy is a common procedure that may be associated with the development of choroidal neovascularization in healthy young females. Further studies should be performed to evaluate this association, but both ophthalmologist and gynecologist should be aware of this potential complication.
AB - Purpose:To report three cases of choroidal neovascularization after hormonal treatment for ovarian stimulation during a fertility therapy.Methods:A comprehensive ophthalmic examination was performed in all cases including best-corrected visual acuity, color fundus examination, fluorescein angiography, and optical coherence tomography.Results:Three females in their thirties developed unilateral acuity vision loss and metamorphopsia. They all were undergoing hormonal supplementation for ovarian stimulation with gonadotropins at the moment of presentation. Intravitreal therapy with ranibizumab was used; all cases showed a significant functional and anatomical improvement.Discussion:Hormonal supplementation for fertility therapy is a common procedure that may be associated with the development of choroidal neovascularization in healthy young females. Further studies should be performed to evaluate this association, but both ophthalmologist and gynecologist should be aware of this potential complication.
KW - GnRH agonist
KW - artificial insemination
KW - choroidal neovascularization
KW - gonadotropins
KW - hormonal supplementation
KW - idiopathic choroidal neovascularization
KW - ranibizumab
KW - sex hormones
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U2 - 10.1097/ICB.0000000000000549
DO - 10.1097/ICB.0000000000000549
M3 - Article
C2 - 28234781
AN - SCOPUS:85063258459
SN - 1935-1089
VL - 13
SP - 162
EP - 166
JO - Retinal Cases and Brief Reports
JF - Retinal Cases and Brief Reports
IS - 2
ER -