HORMONAL SUPPLEMENTATION TRIGGERING CHOROIDAL NEOVASCULARIZATION in HEALTHY YOUNG FEMALES

Rosa Dolz-Marco, Nuria Doménech, Teresa Diago, Javier Montero, Sara García-Canet, Enrique Cervera-Taulet, Roberto Gallego-Pinazo, J. Fernando Arévalo

Research output: Contribution to journalArticle

Abstract

Purpose:To report three cases of choroidal neovascularization after hormonal treatment for ovarian stimulation during a fertility therapy.Methods:A comprehensive ophthalmic examination was performed in all cases including best-corrected visual acuity, color fundus examination, fluorescein angiography, and optical coherence tomography.Results:Three females in their thirties developed unilateral acuity vision loss and metamorphopsia. They all were undergoing hormonal supplementation for ovarian stimulation with gonadotropins at the moment of presentation. Intravitreal therapy with ranibizumab was used; all cases showed a significant functional and anatomical improvement.Discussion:Hormonal supplementation for fertility therapy is a common procedure that may be associated with the development of choroidal neovascularization in healthy young females. Further studies should be performed to evaluate this association, but both ophthalmologist and gynecologist should be aware of this potential complication.

Original languageEnglish (US)
Pages (from-to)162-166
Number of pages5
JournalRetinal Cases and Brief Reports
Volume13
Issue number2
DOIs
StatePublished - Mar 1 2019

Keywords

  • GnRH agonist
  • artificial insemination
  • choroidal neovascularization
  • gonadotropins
  • hormonal supplementation
  • idiopathic choroidal neovascularization
  • ranibizumab
  • sex hormones

ASJC Scopus subject areas

  • Ophthalmology

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  • Cite this

    Dolz-Marco, R., Doménech, N., Diago, T., Montero, J., García-Canet, S., Cervera-Taulet, E., Gallego-Pinazo, R., & Arévalo, J. F. (2019). HORMONAL SUPPLEMENTATION TRIGGERING CHOROIDAL NEOVASCULARIZATION in HEALTHY YOUNG FEMALES. Retinal Cases and Brief Reports, 13(2), 162-166. https://doi.org/10.1097/ICB.0000000000000549