Hormonal effects of high dose naloxone in humans

Martin R. Cohen, Robert M. Cohen, David Pickar, Don Kreger, Cathy McLellan, Dennis L. Murphy

Research output: Contribution to journalArticlepeer-review


Utilizing a double-blind crossover design, the hormonal effects of high dose, 2 mg/kg, were compared to low dose, 0.4 mg (approx. 5 ug/kg), naloxone administration in physically healthy humans. A significant naloxone dose effect on plasma cortisol levels was found (p

Original languageEnglish (US)
Pages (from-to)373-380
Number of pages8
Issue number4
StatePublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Clinical Neurology
  • Neuroscience(all)
  • Cellular and Molecular Neuroscience


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