Homer: A link between neural activity and glutamate receptor function

Bo Xiao, Jian Cheng Tu, Paul F. Worley

Research output: Contribution to journalReview article

Abstract

The proteins of the Homer family bind to proline-rich sequences in group I metabotropic glutamate receptors, inositol trisphosphate receptors, ryanodine receptors, and Shank family proteins. Homer proteins also self associate and function as adaptors to couple interacting proteins. Recent observations indicate a role for Homer complexes in signal transduction, synaptogenesis and receptor trafficking.

Original languageEnglish (US)
Pages (from-to)370-374
Number of pages5
JournalCurrent Opinion in Neurobiology
Volume10
Issue number3
DOIs
StatePublished - Jun 1 2000

ASJC Scopus subject areas

  • Neuroscience(all)

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