HIV type 1 RNA level as a clinical indicator of renal pathology in HIV-infected patients

Michelle Estrella, Derek M. Fine, Joel E. Gallant, M. Hafizur Rahman, Nagapradeep Nagajothi, Lorraine C. Racusen, Paul J. Scheel, Mohamed G. Atta

Research output: Contribution to journalArticle

Abstract

To determine the value of human immunodeficiency virus type 1 (HIV-1) RNA level in distinguishing HIV-associated nephropathy from non-HIV-associated nephropathy renal pathological conditions, we retrospectively compared renal histopathological findings for 86 HIV-infected patients according to HIV-1 RNA levels. We found that HIV-associated nephropathy was unlikely among patients with HIV-1 RNA levels <400 copies/mL. Hypertensive vascular disease surpassed HIV-associated nephropathy as the most common renal pathological finding among the entire cohort. HIV-1 RNA level did not correlate with renal survival.

Original languageEnglish (US)
Pages (from-to)377-380
Number of pages4
JournalClinical Infectious Diseases
Volume43
Issue number3
DOIs
StatePublished - Aug 1 2006

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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