HIV Seroconversion and Disinfection of Injection Equipment among Intravenous Drug Users, Baltimore, Maryland

David Vlahov, Alvaro Muñoz, David D. Celentano, Sylvia Cohn, James C. Anthony, Howard Chiicoat, Kenrad E. Nelson

Research output: Contribution to journalArticlepeer-review

Abstract

To examine the putative protective effect of disinfectant use on HIV seroconversion among intravenous drug users, we conducted a nested case-control study comparing 22 black heterosexual HIV seroconverters with 95 persistent seronegatives matched on gender, use of cocaine, date of study entry, and duration of follow-up. For intravenous drug users who reported using disinfectant all the time, the odds of seroconversion was 0.77 (95% CI: 0.25–2.38) compared with those who reported no use of disinfectants; for those who used disinfectants some of the time, the corresponding odds ratio was 0.91 (95% CI: 0.26–3.31). The odds ratio for use of disinfectant all the time was 0.63 (95% CI: 0.10–3.91) for those injecting at galleries and 1.08 (95% CI: 0.35–3.11) for those not injecting at galleries. These data suggest a limited protective effect of disinfectant use in the field which may be more beneficial to those injecting in shooting galleries.

Original languageEnglish (US)
Pages (from-to)444-446
Number of pages3
JournalEpidemiology
Volume2
Issue number6
DOIs
StatePublished - Nov 1991

Keywords

  • Acquired immunodeficiency syndrome
  • Disinfectants
  • Human immunodeficiency virus
  • Prevention
  • Substance abuse

ASJC Scopus subject areas

  • Epidemiology

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