HIV infection-related tuberculosis: Clinical manifestations and treatment

Timothy R. Sterling, Paul A. Pham, Richard E. Chaisson

Research output: Contribution to journalReview article

Abstract

Several aspects of human immunodeficiency virus (HIV) infection-related tuberculosis (TB) and its treatment differ from those of TB in HIV-uninfected persons. The risk of TB and the clinical and radiographic manifestations of disease are primary examples. Antiretroviral therapy has a profound effect on lowering the risk of TB in HIV-infected persons, but it can also be associated with immune reconstitution inflammatory disease and unmasking of previously subclinical disease. There are also differences in treatment of HIV infection-related TB because of overlapping drug toxicities and drug-drug interactions between antiretroviral therapy and anti-TB therapy.

Original languageEnglish (US)
Pages (from-to)S223-S230
JournalClinical Infectious Diseases
Volume50
Issue numberSUPPL. 3
DOIs
StatePublished - May 15 2010

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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