HIV infection among Uganda women with cervical cancer: A retrospective study

Wilberforce Kigongo Sekirime; Ron Gray

doi:10.1159/000098197

HIV infection among Uganda women with cervical cancer: A retrospective study

Wilberforce Kigongo Sekirime, Ron Gray

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Objective: To assess whether there is an association between HIV and invasive cervical cancer (ICC). Methodology: A case-control study was conducted in Kampala between 1993 and 1995. 116 women with ICC were matched by age and parity with 116 hospital controls. Participants were tested for HIV and interviewed to assess risk factors for ICC and HIV. The association between HIV and ICC was assessed by conditional logistic regression. Results: HIV prevalence was 18% among cases and 15% among controls. The odds of having ICC for HIV-infected patients was 1.27 (95% CI 0.58-2.80) when compared to controls, and the odds of being infected with HIV was higher in ICC patients aged <33 years (OR = 3.81) when compared to controls of similar age. HIV-infected ICC patients were younger (mean age 35.8 years) compared to 46.5 years in the ICC HIV-negative group (p = 0.021). Conclusion: HIV is associated with an earlier onset of ICC.

Original language	English (US)
Pages (from-to)	222-228
Number of pages	7
Journal	Gynecologic and Obstetric Investigation
Volume	63
Issue number	4
DOIs	https://doi.org/10.1159/000098197
State	Published - May 2007

Keywords

Cervical cancer, invasive
HIV

ASJC Scopus subject areas

Reproductive Medicine
Obstetrics and Gynecology

Access to Document

10.1159/000098197

Cite this

@article{0e4ee12578bf429fbbb1f7d9e60527ac,

title = "HIV infection among Uganda women with cervical cancer: A retrospective study",

abstract = "Objective: To assess whether there is an association between HIV and invasive cervical cancer (ICC). Methodology: A case-control study was conducted in Kampala between 1993 and 1995. 116 women with ICC were matched by age and parity with 116 hospital controls. Participants were tested for HIV and interviewed to assess risk factors for ICC and HIV. The association between HIV and ICC was assessed by conditional logistic regression. Results: HIV prevalence was 18% among cases and 15% among controls. The odds of having ICC for HIV-infected patients was 1.27 (95% CI 0.58-2.80) when compared to controls, and the odds of being infected with HIV was higher in ICC patients aged <33 years (OR = 3.81) when compared to controls of similar age. HIV-infected ICC patients were younger (mean age 35.8 years) compared to 46.5 years in the ICC HIV-negative group (p = 0.021). Conclusion: HIV is associated with an earlier onset of ICC.",

keywords = "Cervical cancer, invasive, HIV",

author = "Sekirime, {Wilberforce Kigongo} and Ron Gray",

year = "2007",

month = may,

doi = "10.1159/000098197",

language = "English (US)",

volume = "63",

pages = "222--228",

journal = "Gynecologic and Obstetric Investigation",

issn = "0378-7346",

publisher = "S. Karger AG",

number = "4",

}

TY - JOUR

T1 - HIV infection among Uganda women with cervical cancer

T2 - A retrospective study

AU - Sekirime, Wilberforce Kigongo

AU - Gray, Ron

PY - 2007/5

Y1 - 2007/5

N2 - Objective: To assess whether there is an association between HIV and invasive cervical cancer (ICC). Methodology: A case-control study was conducted in Kampala between 1993 and 1995. 116 women with ICC were matched by age and parity with 116 hospital controls. Participants were tested for HIV and interviewed to assess risk factors for ICC and HIV. The association between HIV and ICC was assessed by conditional logistic regression. Results: HIV prevalence was 18% among cases and 15% among controls. The odds of having ICC for HIV-infected patients was 1.27 (95% CI 0.58-2.80) when compared to controls, and the odds of being infected with HIV was higher in ICC patients aged <33 years (OR = 3.81) when compared to controls of similar age. HIV-infected ICC patients were younger (mean age 35.8 years) compared to 46.5 years in the ICC HIV-negative group (p = 0.021). Conclusion: HIV is associated with an earlier onset of ICC.

AB - Objective: To assess whether there is an association between HIV and invasive cervical cancer (ICC). Methodology: A case-control study was conducted in Kampala between 1993 and 1995. 116 women with ICC were matched by age and parity with 116 hospital controls. Participants were tested for HIV and interviewed to assess risk factors for ICC and HIV. The association between HIV and ICC was assessed by conditional logistic regression. Results: HIV prevalence was 18% among cases and 15% among controls. The odds of having ICC for HIV-infected patients was 1.27 (95% CI 0.58-2.80) when compared to controls, and the odds of being infected with HIV was higher in ICC patients aged <33 years (OR = 3.81) when compared to controls of similar age. HIV-infected ICC patients were younger (mean age 35.8 years) compared to 46.5 years in the ICC HIV-negative group (p = 0.021). Conclusion: HIV is associated with an earlier onset of ICC.

KW - Cervical cancer, invasive

KW - HIV

UR - http://www.scopus.com/inward/record.url?scp=34248342130&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=34248342130&partnerID=8YFLogxK

U2 - 10.1159/000098197

DO - 10.1159/000098197

M3 - Article

C2 - 17191009

AN - SCOPUS:34248342130

SN - 0378-7346

VL - 63

SP - 222

EP - 228

JO - Gynecologic and Obstetric Investigation

JF - Gynecologic and Obstetric Investigation

IS - 4

ER -

HIV infection among Uganda women with cervical cancer: A retrospective study

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this