TY - JOUR
T1 - HIV incidence, retention rate, and baseline predictors of HIV incidence and retention in a prospective cohort study of injection drug users in Xinjiang, China
AU - Zhang, Yuanzhi
AU - Shan, Hua
AU - Trizzino, Jennifer
AU - Ruan, Yuhua
AU - Beauchamp, Geetha
AU - Mâsse, Benoît
AU - Ma, Jun
AU - Rui, Baoling
AU - Wang, Jun
AU - Liu, Minsheng
AU - Wang, Yunxia
AU - He, Yixin
AU - Poundstone, Katharine
AU - Jiang, Yan
AU - Jackson, J. Brooks
AU - Shao, Yiming
PY - 2007/7
Y1 - 2007/7
N2 - Objective: To determine HIV seroincidence, study participant retention rate, and baseline predictors of HIV incidence and study retention among high-risk injection drug users (IDUs) in Xinjiang, China. Methods: A total of 508 eligible seronegative high-risk IDUs were enrolled. Study participants were tested for HIV-1 and counseled at the baseline, 6-month, and 12-month follow-up visits. Sociodemographic and behavioral data were collected during each study visit. The HIV-1 incidence rate and the retention rate were analyzed as a function of sociodemographic, behavioral, and recruitment variables. Results: At 12 months of follow-up, the HIV-1 incidence rate was 8.8 per 100 person-years (95% CI 6.3-12.0%) and the participant retention rate was 93%. Marital status at baseline was the only predictor of HIV incidence. No baseline variables were predictive of study retention. Conclusions: HIV incidence is high among IDUs in Xinjiang, China. Baseline predictors of incidence and retention were minimal. The participant retention rate in this study is promising for the undertaking of future HIV intervention studies.
AB - Objective: To determine HIV seroincidence, study participant retention rate, and baseline predictors of HIV incidence and study retention among high-risk injection drug users (IDUs) in Xinjiang, China. Methods: A total of 508 eligible seronegative high-risk IDUs were enrolled. Study participants were tested for HIV-1 and counseled at the baseline, 6-month, and 12-month follow-up visits. Sociodemographic and behavioral data were collected during each study visit. The HIV-1 incidence rate and the retention rate were analyzed as a function of sociodemographic, behavioral, and recruitment variables. Results: At 12 months of follow-up, the HIV-1 incidence rate was 8.8 per 100 person-years (95% CI 6.3-12.0%) and the participant retention rate was 93%. Marital status at baseline was the only predictor of HIV incidence. No baseline variables were predictive of study retention. Conclusions: HIV incidence is high among IDUs in Xinjiang, China. Baseline predictors of incidence and retention were minimal. The participant retention rate in this study is promising for the undertaking of future HIV intervention studies.
KW - China
KW - HIV
KW - IDUs
KW - Incidence
KW - Retention
KW - Xinjiang
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U2 - 10.1016/j.ijid.2006.09.001
DO - 10.1016/j.ijid.2006.09.001
M3 - Article
C2 - 17321184
AN - SCOPUS:34347204435
SN - 1201-9712
VL - 11
SP - 318
EP - 323
JO - International Journal of Infectious Diseases
JF - International Journal of Infectious Diseases
IS - 4
ER -