HIV-associated neurologic disease incidence changes

Multicenter AIDS Cohort Study, 1990-1998

Ned Sacktor, R. H. Lyles, Richard Skolasky, C. Kleeberger, O. A. Selnes, E. N. Miller, J. T. Becker, B. Cohen, Justin Charles McArthur

Research output: Contribution to journalArticle

Abstract

This study examined the temporal trends in the incidence rates of HIV dementia, cryptococcal meningitis, toxoplasmosis, progressive multifocal leukoencephalopathy, and CNS lymphoma from January 1990 to December 1998 in the Multicenter AIDS Cohort Study. The incidence rates for HIV dementia, cryptococcal meningitis, and lymphoma decreased following the introduction of highly active antiretroviral therapy (HAART). The proportion of new cases of HIV dementia with a CD4 count in a higher range (i.e., 201 to 350) since 1996 may be increasing.

Original languageEnglish (US)
Pages (from-to)257-260
Number of pages4
JournalNeurology
Volume56
Issue number2
StatePublished - Jan 23 2001

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AIDS Dementia Complex
Nervous System Diseases
Cryptococcal Meningitis
Acquired Immunodeficiency Syndrome
Cohort Studies
HIV
Lymphoma
Incidence
Progressive Multifocal Leukoencephalopathy
Toxoplasmosis
Highly Active Antiretroviral Therapy
CD4 Lymphocyte Count

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

HIV-associated neurologic disease incidence changes : Multicenter AIDS Cohort Study, 1990-1998. / Sacktor, Ned; Lyles, R. H.; Skolasky, Richard; Kleeberger, C.; Selnes, O. A.; Miller, E. N.; Becker, J. T.; Cohen, B.; McArthur, Justin Charles.

In: Neurology, Vol. 56, No. 2, 23.01.2001, p. 257-260.

Research output: Contribution to journalArticle

Sacktor, N, Lyles, RH, Skolasky, R, Kleeberger, C, Selnes, OA, Miller, EN, Becker, JT, Cohen, B & McArthur, JC 2001, 'HIV-associated neurologic disease incidence changes: Multicenter AIDS Cohort Study, 1990-1998', Neurology, vol. 56, no. 2, pp. 257-260.
Sacktor N, Lyles RH, Skolasky R, Kleeberger C, Selnes OA, Miller EN et al. HIV-associated neurologic disease incidence changes: Multicenter AIDS Cohort Study, 1990-1998. Neurology. 2001 Jan 23;56(2):257-260.
Sacktor, Ned ; Lyles, R. H. ; Skolasky, Richard ; Kleeberger, C. ; Selnes, O. A. ; Miller, E. N. ; Becker, J. T. ; Cohen, B. ; McArthur, Justin Charles. / HIV-associated neurologic disease incidence changes : Multicenter AIDS Cohort Study, 1990-1998. In: Neurology. 2001 ; Vol. 56, No. 2. pp. 257-260.
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