HIV-1/HIV-2 versus samhd1 restriction: A tale of two viruses

Wei Wei; Xiao Fang Yu

doi:10.1016/j.chom.2014.12.005

HIV-1/HIV-2 versus samhd1 restriction: A tale of two viruses

Wei Wei, Xiao Fang Yu

Bloomberg School of Public Health

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

The deoxynucleoside triphosphate triphosphohydrolase SAMHD1 is a myeloid cell-specific retroviral restriction factor that can be inactivated by viral protein Vpx from HIV-2 and certain SIV. In this issue of Cell Host & Microbe, Kyei et al. (2015) report that cyclin L2 enhances HIV-1 infection in macrophages by regulating SAMHD1.

Original language	English (US)
Pages (from-to)	8-9
Number of pages	2
Journal	Cell Host and Microbe
Volume	17
Issue number	1
DOIs	https://doi.org/10.1016/j.chom.2014.12.005
State	Published - Jan 14 2015

ASJC Scopus subject areas

Parasitology
Microbiology
Virology

Access to Document

10.1016/j.chom.2014.12.005

Cite this

@article{772f080f1aaa4f83a497c2c2939f291e,

title = "HIV-1/HIV-2 versus samhd1 restriction: A tale of two viruses",

abstract = "The deoxynucleoside triphosphate triphosphohydrolase SAMHD1 is a myeloid cell-specific retroviral restriction factor that can be inactivated by viral protein Vpx from HIV-2 and certain SIV. In this issue of Cell Host & Microbe, Kyei et al. (2015) report that cyclin L2 enhances HIV-1 infection in macrophages by regulating SAMHD1.",

author = "Wei Wei and Yu, {Xiao Fang}",

note = "Funding Information: This work was supported in part by funding from the Chinese Ministry of Science and Technology (numbers 2012CB911100, 2012CB911103, and 2013ZX0001-005) and funding from Tianjin University. Publisher Copyright: {\textcopyright} 2015 Elsevier Inc.",

year = "2015",

month = jan,

day = "14",

doi = "10.1016/j.chom.2014.12.005",

language = "English (US)",

volume = "17",

pages = "8--9",

journal = "Cell Host and Microbe",

issn = "1931-3128",

publisher = "Cell Press",

number = "1",

}

TY - JOUR

T1 - HIV-1/HIV-2 versus samhd1 restriction

T2 - A tale of two viruses

AU - Wei, Wei

AU - Yu, Xiao Fang

N1 - Funding Information: This work was supported in part by funding from the Chinese Ministry of Science and Technology (numbers 2012CB911100, 2012CB911103, and 2013ZX0001-005) and funding from Tianjin University. Publisher Copyright: © 2015 Elsevier Inc.

PY - 2015/1/14

Y1 - 2015/1/14

N2 - The deoxynucleoside triphosphate triphosphohydrolase SAMHD1 is a myeloid cell-specific retroviral restriction factor that can be inactivated by viral protein Vpx from HIV-2 and certain SIV. In this issue of Cell Host & Microbe, Kyei et al. (2015) report that cyclin L2 enhances HIV-1 infection in macrophages by regulating SAMHD1.

AB - The deoxynucleoside triphosphate triphosphohydrolase SAMHD1 is a myeloid cell-specific retroviral restriction factor that can be inactivated by viral protein Vpx from HIV-2 and certain SIV. In this issue of Cell Host & Microbe, Kyei et al. (2015) report that cyclin L2 enhances HIV-1 infection in macrophages by regulating SAMHD1.

UR - http://www.scopus.com/inward/record.url?scp=84920885492&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84920885492&partnerID=8YFLogxK

U2 - 10.1016/j.chom.2014.12.005

DO - 10.1016/j.chom.2014.12.005

M3 - Short survey

C2 - 25590755

AN - SCOPUS:84920885492

SN - 1931-3128

VL - 17

SP - 8

EP - 9

JO - Cell Host and Microbe

JF - Cell Host and Microbe

IS - 1

ER -

HIV-1/HIV-2 versus samhd1 restriction: A tale of two viruses

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this