Histopathologie des Endometriumkarzinoms

Translated title of the contribution: Histopathology of endometrial carcinoma

Robert J Kurman, T. G. McConnell

Research output: Contribution to journalArticle

Abstract

Endometrial carcinoma is a common malignancy with numerous histopathologic variants. The majority of cases are classified as type I tumors, show endometrioid morphology, are low grade and low stage and have excellent 5-year survival. Type II tumors are much less common, are predominantly serous carcinomas and are uniformly highly aggressive. This clinical dichotomy is reflected in and supported by reproducible molecular genetic alterations specific to each type. Less is known about the underlying genetic mutations for the rarer type II tumors and it is yet to be determined if clear cell carcinoma of the endometrium will be classifiable as type I, type II or will remain an outlier in this classification.

Original languageGerman
Pages (from-to)1239-1242
Number of pages4
JournalOnkologe
Volume15
Issue number12
DOIs
StatePublished - Dec 2009

Fingerprint

Endometrial Neoplasms
Neoplasms
Molecular Biology
Carcinoma
Mutation

Keywords

  • Classification
  • Endometrial carcinoma
  • Histopathology
  • Type I tumor
  • Type II tumor

ASJC Scopus subject areas

  • Oncology
  • Hematology

Cite this

Histopathologie des Endometriumkarzinoms. / Kurman, Robert J; McConnell, T. G.

In: Onkologe, Vol. 15, No. 12, 12.2009, p. 1239-1242.

Research output: Contribution to journalArticle

Kurman, Robert J ; McConnell, T. G. / Histopathologie des Endometriumkarzinoms. In: Onkologe. 2009 ; Vol. 15, No. 12. pp. 1239-1242.
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