Histopathologic changes after pericardial patch tracheoplasty

Alan T.L. Cheng, Carl L. Bacher, Lauren D. Holinger, Michael E. Dunham, Constantine Mavroudis, Franh Gonzalez-Cnissi

Research output: Contribution to journalArticle

Abstract

Pericardial patch tracheoplasty has been used for surgical correction of long-segment congenital tracheal stenosis caused by complete tracheal rings in infants. The case histories of 2 infants with descriptions of the histopathologic changes in their respective tracheas are presented. Complete reepithelialization of the graft site with ciliated pseudostratified columnar epithelium was found, suggesting the likelihood of normal mucociliary flow in the trachea. The pericardial patches were replaced by mature scar tissue in the graft site, establishing a functional tracheal lumen. Wound healing in the trachea is reviewed. Obstruction by exuberant granulation tissue is an ongoing concern. Pericardium continues to be an important option as graft material for tracheal reconstruction in infants with long-segment congenital tracheal stenosis.

Original languageEnglish (US)
Pages (from-to)1069-1072
Number of pages4
JournalArchives of Otolaryngology - Head and Neck Surgery
Volume123
Issue number10
DOIs
StatePublished - Jan 1 1997
Externally publishedYes

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Trachea
Transplants
Granulation Tissue
Pericardium
Wound Healing
Cicatrix
Epithelium
Tracheal agenesis

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

Cite this

Histopathologic changes after pericardial patch tracheoplasty. / Cheng, Alan T.L.; Bacher, Carl L.; Holinger, Lauren D.; Dunham, Michael E.; Mavroudis, Constantine; Gonzalez-Cnissi, Franh.

In: Archives of Otolaryngology - Head and Neck Surgery, Vol. 123, No. 10, 01.01.1997, p. 1069-1072.

Research output: Contribution to journalArticle

Cheng, Alan T.L. ; Bacher, Carl L. ; Holinger, Lauren D. ; Dunham, Michael E. ; Mavroudis, Constantine ; Gonzalez-Cnissi, Franh. / Histopathologic changes after pericardial patch tracheoplasty. In: Archives of Otolaryngology - Head and Neck Surgery. 1997 ; Vol. 123, No. 10. pp. 1069-1072.
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