TY - JOUR
T1 - His bundle pacing
T2 - Hemodynamics and clinical outcomes
AU - Patel, Brijesh
AU - Garg, Jalaj
AU - Chaudhary, Rahul
AU - Sablani, Naveen
AU - Gupta, Rahul
AU - Shah, Mahek
AU - Nazir, Talha
AU - Bozorgnia, Babak
AU - Natale, Andrea
PY - 2018/1/1
Y1 - 2018/1/1
N2 - From 1993 to 2009, nearly 2.9 million pacemakers were implanted in the United States; the majority of which were dual-chamber pacemakers. One of the major physiologic advantages of dual-chamber pacing over singlechamber ventricular pacing is atrioventricular synchrony, which prevents the pacemaker syndrome. However, patients who are pacemaker dependent or use right ventricle (RV) apical pacing more than 40% of the time are at a risk of developing heart failure from electromechanical dyssynchrony. Studies have also shown that RV pacing results in nonphysiological activation of the left ventricle, leading to adverse clinical outcomes. Hence, alternative pacing sites, including the RV outflow tract, the high-RV septal region, bi-ventricular pacing, or His bundle pacing, have been explored for a better physiological electromechanical coupling of the ventricles. Although His bundle pacing has gained attention due to favorable data and clinical outcomes, it has not gained widespread acceptance into clinical practice. Hence, we aim to review the current experience with His bundle pacing and its clinical implications in this article.
AB - From 1993 to 2009, nearly 2.9 million pacemakers were implanted in the United States; the majority of which were dual-chamber pacemakers. One of the major physiologic advantages of dual-chamber pacing over singlechamber ventricular pacing is atrioventricular synchrony, which prevents the pacemaker syndrome. However, patients who are pacemaker dependent or use right ventricle (RV) apical pacing more than 40% of the time are at a risk of developing heart failure from electromechanical dyssynchrony. Studies have also shown that RV pacing results in nonphysiological activation of the left ventricle, leading to adverse clinical outcomes. Hence, alternative pacing sites, including the RV outflow tract, the high-RV septal region, bi-ventricular pacing, or His bundle pacing, have been explored for a better physiological electromechanical coupling of the ventricles. Although His bundle pacing has gained attention due to favorable data and clinical outcomes, it has not gained widespread acceptance into clinical practice. Hence, we aim to review the current experience with His bundle pacing and its clinical implications in this article.
KW - His bundle
KW - Nonselective His bundle pacing
KW - QRS duration
KW - Selective His bundle pacing
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U2 - 10.1097/CRD.0000000000000191
DO - 10.1097/CRD.0000000000000191
M3 - Article
C2 - 29608497
AN - SCOPUS:85051748964
SN - 1061-5377
VL - 26
SP - 201
EP - 206
JO - Cardiology in Review
JF - Cardiology in Review
IS - 4
ER -