Abstract
This series of experiments investigated the effects of dorsal and ventral hippocampal lesions on taste aversion learning. Although damage to the hippocampus did not affect the acquisition of a taste aversion when the conditioning procedure used a relatively standard interval between taste and illness, both types of lesions produced a deficit in taste aversion when a long interval (3 h) was interposed between taste exposure and induction of illness. In the same subjects, trace fear conditioning was selectively impaired by ventral lesions, whereas water maze performance was selectively impaired by dorsal lesions. The results replicate past dissociations of dorsal and ventral hippocampal function, and also suggest that the hippocampus has a less differentiated role in long-trace taste aversion learning.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 103-107 |
| Number of pages | 5 |
| Journal | Physiology and Behavior |
| Volume | 98 |
| Issue number | 1-2 |
| DOIs | |
| State | Published - Aug 4 2009 |
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Keywords
- Delay
- Freezing
- Memory
- Spatial
- Trace
ASJC Scopus subject areas
- Behavioral Neuroscience
- Experimental and Cognitive Psychology
Cite this
Hippocampal lesions interfere with long-trace taste aversion conditioning. / Koh, Ming Teng; Wheeler, Daniel S.; Gallagher, Michela.
In: Physiology and Behavior, Vol. 98, No. 1-2, 04.08.2009, p. 103-107.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Hippocampal lesions interfere with long-trace taste aversion conditioning
AU - Koh, Ming Teng
AU - Wheeler, Daniel S.
AU - Gallagher, Michela
PY - 2009/8/4
Y1 - 2009/8/4
N2 - This series of experiments investigated the effects of dorsal and ventral hippocampal lesions on taste aversion learning. Although damage to the hippocampus did not affect the acquisition of a taste aversion when the conditioning procedure used a relatively standard interval between taste and illness, both types of lesions produced a deficit in taste aversion when a long interval (3 h) was interposed between taste exposure and induction of illness. In the same subjects, trace fear conditioning was selectively impaired by ventral lesions, whereas water maze performance was selectively impaired by dorsal lesions. The results replicate past dissociations of dorsal and ventral hippocampal function, and also suggest that the hippocampus has a less differentiated role in long-trace taste aversion learning.
AB - This series of experiments investigated the effects of dorsal and ventral hippocampal lesions on taste aversion learning. Although damage to the hippocampus did not affect the acquisition of a taste aversion when the conditioning procedure used a relatively standard interval between taste and illness, both types of lesions produced a deficit in taste aversion when a long interval (3 h) was interposed between taste exposure and induction of illness. In the same subjects, trace fear conditioning was selectively impaired by ventral lesions, whereas water maze performance was selectively impaired by dorsal lesions. The results replicate past dissociations of dorsal and ventral hippocampal function, and also suggest that the hippocampus has a less differentiated role in long-trace taste aversion learning.
KW - Delay
KW - Freezing
KW - Memory
KW - Spatial
KW - Trace
UR - http://www.scopus.com/inward/record.url?scp=67649499847&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67649499847&partnerID=8YFLogxK
U2 - 10.1016/j.physbeh.2009.04.017
DO - 10.1016/j.physbeh.2009.04.017
M3 - Article
C2 - 19394353
AN - SCOPUS:67649499847
VL - 98
SP - 103
EP - 107
JO - Physiology and Behavior
JF - Physiology and Behavior
SN - 0031-9384
IS - 1-2
ER -