Hip migration percentage in children with cerebral palsy treated with botulinum toxin type A

Frank S. Pidcock; David E. Fish; Doug Johnson-Greene; Isabel Borras; John McGready; Charles E. Silberstein

doi:10.1016/j.apmr.2004.03.034

Hip migration percentage in children with cerebral palsy treated with botulinum toxin type A

Frank S. Pidcock, David E. Fish, Doug Johnson-Greene, Isabel Borras, John McGready, Charles E. Silberstein

Research output: Contribution to journal › Article › peer-review

33 Scopus citations

Abstract

Objective: To determine hip radiographic findings in children with cerebral palsy (CP) treated with botulinum toxin type A (BTX-A). Design: Retrospective chart review with correlation to radiographic findings. Setting: Academic center. Participants: Sixteen subjects with CP. Intervention: BTX-A treatment to adductor muscles. Main Outcome Measure: The Reimers hip migration percentage before and after BTX-A. Results: Thirty-two hips in 16 children with CP were treated. We examined the effect of initial migration percentage and initial migration percentage age on the change in migration percentage after BTX-A injection. A significant effect for initial migration percentage (<30% or ≥30%; F=19.05, P<.001) and a significant interaction between initial migration percentage and initial migration percentage age (F=7.5, P<.01) was noted. Initial migration percentage age (≤24mo or >24mo) was not significant (F=.95, P=.34). Patients who had an initial migration percentage of 30% or more and were less than 24 months old were more likely to have a decrease in migration percentage after BTX-A injection compared with patients who were older than 24 months and who had an initial migration percentage of 30% or more. Conclusions: Improvement in hip migration percentage after BTX-A injection is a function of age and the initial migration percentage. BTX-A injections to adductor muscles may be beneficial for some children with CP.

Original language	English (US)
Pages (from-to)	431-435
Number of pages	5
Journal	Archives of physical medicine and rehabilitation
Volume	86
Issue number	3
DOIs	https://doi.org/10.1016/j.apmr.2004.03.034
State	Published - Mar 2005

Keywords

Botulinum toxin type A
Cerebral palsy
Hip
Rehabilitation

ASJC Scopus subject areas

Physical Therapy, Sports Therapy and Rehabilitation
Rehabilitation

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10.1016/j.apmr.2004.03.034

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@article{748f12cefb6742058484d9c49fabb24d,

title = "Hip migration percentage in children with cerebral palsy treated with botulinum toxin type A",

abstract = "Objective: To determine hip radiographic findings in children with cerebral palsy (CP) treated with botulinum toxin type A (BTX-A). Design: Retrospective chart review with correlation to radiographic findings. Setting: Academic center. Participants: Sixteen subjects with CP. Intervention: BTX-A treatment to adductor muscles. Main Outcome Measure: The Reimers hip migration percentage before and after BTX-A. Results: Thirty-two hips in 16 children with CP were treated. We examined the effect of initial migration percentage and initial migration percentage age on the change in migration percentage after BTX-A injection. A significant effect for initial migration percentage (<30% or ≥30%; F=19.05, P<.001) and a significant interaction between initial migration percentage and initial migration percentage age (F=7.5, P<.01) was noted. Initial migration percentage age (≤24mo or >24mo) was not significant (F=.95, P=.34). Patients who had an initial migration percentage of 30% or more and were less than 24 months old were more likely to have a decrease in migration percentage after BTX-A injection compared with patients who were older than 24 months and who had an initial migration percentage of 30% or more. Conclusions: Improvement in hip migration percentage after BTX-A injection is a function of age and the initial migration percentage. BTX-A injections to adductor muscles may be beneficial for some children with CP.",

keywords = "Botulinum toxin type A, Cerebral palsy, Hip, Rehabilitation",

author = "Pidcock, {Frank S.} and Fish, {David E.} and Doug Johnson-Greene and Isabel Borras and John McGready and Silberstein, {Charles E.}",

note = "Funding Information: Supported by Allergan honoraria (unrestricted educational grant). Funding Information: An organization, with which 1 or more of the authors is associated, has received or will receive financial benefits from a commercial party having a direct financial interest in the results of the research supporting this article. Pidcock has received unrestricted educational grants from Allergen, has been a coinvestigator on a multicenter clinical trial sponsored by Allergen, and has attended educational meetings sponsored by Allergen. Fish has been a consultant to Allergen and has spoken for Allergen. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.",

year = "2005",

month = mar,

doi = "10.1016/j.apmr.2004.03.034",

language = "English (US)",

volume = "86",

pages = "431--435",

journal = "Archives of physical medicine and rehabilitation",

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publisher = "W.B. Saunders Ltd",

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TY - JOUR

T1 - Hip migration percentage in children with cerebral palsy treated with botulinum toxin type A

AU - Pidcock, Frank S.

AU - Fish, David E.

AU - Johnson-Greene, Doug

AU - Borras, Isabel

AU - McGready, John

AU - Silberstein, Charles E.

N1 - Funding Information: Supported by Allergan honoraria (unrestricted educational grant). Funding Information: An organization, with which 1 or more of the authors is associated, has received or will receive financial benefits from a commercial party having a direct financial interest in the results of the research supporting this article. Pidcock has received unrestricted educational grants from Allergen, has been a coinvestigator on a multicenter clinical trial sponsored by Allergen, and has attended educational meetings sponsored by Allergen. Fish has been a consultant to Allergen and has spoken for Allergen. Copyright: Copyright 2018 Elsevier B.V., All rights reserved.

PY - 2005/3

Y1 - 2005/3

N2 - Objective: To determine hip radiographic findings in children with cerebral palsy (CP) treated with botulinum toxin type A (BTX-A). Design: Retrospective chart review with correlation to radiographic findings. Setting: Academic center. Participants: Sixteen subjects with CP. Intervention: BTX-A treatment to adductor muscles. Main Outcome Measure: The Reimers hip migration percentage before and after BTX-A. Results: Thirty-two hips in 16 children with CP were treated. We examined the effect of initial migration percentage and initial migration percentage age on the change in migration percentage after BTX-A injection. A significant effect for initial migration percentage (<30% or ≥30%; F=19.05, P<.001) and a significant interaction between initial migration percentage and initial migration percentage age (F=7.5, P<.01) was noted. Initial migration percentage age (≤24mo or >24mo) was not significant (F=.95, P=.34). Patients who had an initial migration percentage of 30% or more and were less than 24 months old were more likely to have a decrease in migration percentage after BTX-A injection compared with patients who were older than 24 months and who had an initial migration percentage of 30% or more. Conclusions: Improvement in hip migration percentage after BTX-A injection is a function of age and the initial migration percentage. BTX-A injections to adductor muscles may be beneficial for some children with CP.

AB - Objective: To determine hip radiographic findings in children with cerebral palsy (CP) treated with botulinum toxin type A (BTX-A). Design: Retrospective chart review with correlation to radiographic findings. Setting: Academic center. Participants: Sixteen subjects with CP. Intervention: BTX-A treatment to adductor muscles. Main Outcome Measure: The Reimers hip migration percentage before and after BTX-A. Results: Thirty-two hips in 16 children with CP were treated. We examined the effect of initial migration percentage and initial migration percentage age on the change in migration percentage after BTX-A injection. A significant effect for initial migration percentage (<30% or ≥30%; F=19.05, P<.001) and a significant interaction between initial migration percentage and initial migration percentage age (F=7.5, P<.01) was noted. Initial migration percentage age (≤24mo or >24mo) was not significant (F=.95, P=.34). Patients who had an initial migration percentage of 30% or more and were less than 24 months old were more likely to have a decrease in migration percentage after BTX-A injection compared with patients who were older than 24 months and who had an initial migration percentage of 30% or more. Conclusions: Improvement in hip migration percentage after BTX-A injection is a function of age and the initial migration percentage. BTX-A injections to adductor muscles may be beneficial for some children with CP.

KW - Botulinum toxin type A

KW - Cerebral palsy

KW - Hip

KW - Rehabilitation

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JO - Archives of physical medicine and rehabilitation

JF - Archives of physical medicine and rehabilitation

IS - 3

ER -

Hip migration percentage in children with cerebral palsy treated with botulinum toxin type A

Abstract

Keywords

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