Hilar cholangiocarcinoma: Tumor depth as a predictor of outcome

Mechteld C. De Jong, Seung Mo Hong, Mathew M. Augustine, Michael S Goggins, Christopher Wolfgang, Kenzo Hirose, Richard D. Schulick, Michael A. Choti, Robert A Anders, Timothy M. Pawlik

Research output: Contribution to journalArticle

Abstract

Background: The American Joint Committee on Cancer staging system for hilar cholangiocarcinoma may be inaccurate because the bile duct lacks discrete tissue boundaries. Objectives: To examine the accuracy of the American Joint Committee on Cancer staging schemes and to determine the prognostic implications of tumor depth. Design, Setting, and Patients: From January 1, 1987, through December 31, 2009, there were 106 patients who underwent resection of hilar cholangiocarcinoma who had pathologic slides available for re-review. Main Outcome Measures: Tumor depth and overall survival. Results: Overall median survival was 19.9 months. The 6th and 7th editions of the T-classification criteria were unable to discriminate among T1, T2, and T3 lesions (P>.05 for all). Median survival was associated with the invasion depth of the tumor (≥5 mm vs

Original languageEnglish (US)
Pages (from-to)697-703
Number of pages7
JournalArchives of Surgery
Volume146
Issue number6
DOIs
StatePublished - Jun 2011

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Klatskin Tumor
Neoplasm Staging
Survival
Neoplasms
Bile Ducts
Outcome Assessment (Health Care)

ASJC Scopus subject areas

  • Surgery

Cite this

De Jong, M. C., Hong, S. M., Augustine, M. M., Goggins, M. S., Wolfgang, C., Hirose, K., ... Pawlik, T. M. (2011). Hilar cholangiocarcinoma: Tumor depth as a predictor of outcome. Archives of Surgery, 146(6), 697-703. https://doi.org/10.1001/archsurg.2011.122

Hilar cholangiocarcinoma : Tumor depth as a predictor of outcome. / De Jong, Mechteld C.; Hong, Seung Mo; Augustine, Mathew M.; Goggins, Michael S; Wolfgang, Christopher; Hirose, Kenzo; Schulick, Richard D.; Choti, Michael A.; Anders, Robert A; Pawlik, Timothy M.

In: Archives of Surgery, Vol. 146, No. 6, 06.2011, p. 697-703.

Research output: Contribution to journalArticle

De Jong, MC, Hong, SM, Augustine, MM, Goggins, MS, Wolfgang, C, Hirose, K, Schulick, RD, Choti, MA, Anders, RA & Pawlik, TM 2011, 'Hilar cholangiocarcinoma: Tumor depth as a predictor of outcome', Archives of Surgery, vol. 146, no. 6, pp. 697-703. https://doi.org/10.1001/archsurg.2011.122
De Jong, Mechteld C. ; Hong, Seung Mo ; Augustine, Mathew M. ; Goggins, Michael S ; Wolfgang, Christopher ; Hirose, Kenzo ; Schulick, Richard D. ; Choti, Michael A. ; Anders, Robert A ; Pawlik, Timothy M. / Hilar cholangiocarcinoma : Tumor depth as a predictor of outcome. In: Archives of Surgery. 2011 ; Vol. 146, No. 6. pp. 697-703.
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