Injuries are the leading cause of death in the United States from early childhood until about age 45. Motor vehicles kill more Americans age 1 to 34 than any other source of injury or disease. The death rate per million person miles of travel for car travel is about 200 times the rate for passengers on trains and about 350 times the rate for airline passengers. Motor vehicles also represent the largest single cause of occupational fatilities. What is needed is to direct to motor vehicle-related injury the attention and resources that are commensurate with the human losses.