The DNA of the human serum amyloid A (SAA) gene GSAA1 contains several repetitive regions within its introns. We have studied length variations al one such region in the 2nd intron by selective amplification using the polymerase chain reaction (PCR) and defined oligonucleotide primers. The lengths of the repetitive regions frequently differ between individual chromosomes and can be transmitted as Mendelian markers, making them useful for genetic linkage analysis.
|Original language||English (US)|
|Number of pages||4|
|Journal||Scandinavian Journal of Immunology|
|State||Published - Apr 1991|
ASJC Scopus subject areas