Highly Polymorphic Domains of the Human Serum Amyloid A (SAA) Gene GSAA1

G. H. SACK; C. C. TALBOT

doi:10.1111/j.1365-3083.1991.tb01797.x

Highly Polymorphic Domains of the Human Serum Amyloid A (SAA) Gene GSAA1

G. H. SACK, C. C. TALBOT

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

The DNA of the human serum amyloid A (SAA) gene GSAA1 contains several repetitive regions within its introns. We have studied length variations al one such region in the 2nd intron by selective amplification using the polymerase chain reaction (PCR) and defined oligonucleotide primers. The lengths of the repetitive regions frequently differ between individual chromosomes and can be transmitted as Mendelian markers, making them useful for genetic linkage analysis.

Original language	English (US)
Pages (from-to)	485-488
Number of pages	4
Journal	Scandinavian Journal of Immunology
Volume	33
Issue number	4
DOIs	https://doi.org/10.1111/j.1365-3083.1991.tb01797.x
State	Published - Apr 1991
Externally published	Yes

ASJC Scopus subject areas

Immunology

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abstract = "The DNA of the human serum amyloid A (SAA) gene GSAA1 contains several repetitive regions within its introns. We have studied length variations al one such region in the 2nd intron by selective amplification using the polymerase chain reaction (PCR) and defined oligonucleotide primers. The lengths of the repetitive regions frequently differ between individual chromosomes and can be transmitted as Mendelian markers, making them useful for genetic linkage analysis.",

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AB - The DNA of the human serum amyloid A (SAA) gene GSAA1 contains several repetitive regions within its introns. We have studied length variations al one such region in the 2nd intron by selective amplification using the polymerase chain reaction (PCR) and defined oligonucleotide primers. The lengths of the repetitive regions frequently differ between individual chromosomes and can be transmitted as Mendelian markers, making them useful for genetic linkage analysis.

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Highly Polymorphic Domains of the Human Serum Amyloid A (SAA) Gene GSAA1

Abstract

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