High-signal T2 changes of the bone marrow of the foot and ankle in children: Red marrow or traumatic changes?

Nogah Shabshin, Mark E. Schweitzer, William B. Morrison, John A. Carrino, Marc S. Keller, Leslie E. Grissom

Research output: Contribution to journalArticle

Abstract

Background: High-signal T2-weighted bone marrow changes can be found in both bone marrow edema and hematopoietic marrow and are often seen on pediatric MR images of the feet and ankle. Objective: To evaluate whether high-signal T2 changes of the bone marrow seen on pediatric MRI of feet and ankles represent residual hematopoietic marrow. Materials and methods: A total of 402 bones in 41 pediatric MRI studies of feet and ankles (34 children, 1-18 years) were reviewed by two observers who were blinded to the patients' ages. The studies were reviewed for the presence of high-signal changes of the bone marrow on sagittal fluid-sensitive images. The frequency and location of these foci were correlated with the patients' ages. Results: High-signal T2 changes of the bone marrow were seen in 45/402 bones (11%) and in 24/41 patients younger than 16 years (59%). The changes were most commonly located in the calcaneus (54%), followed by the talus (35%) and navicular bone (35%), invariably at the endosteal surface. In 16 ankles, such foci were seen in the feet but not in the distal tibia/fibula. Symmetric presence (two ankles) or absence (four ankles) of high-signal marrow were seen in six of seven patients with bilateral ankles. Conclusion: High-signal T2 changes of the bone marrow in pediatric feet and ankle MRIs have a symmetric, fairly consistent pattern and disappear after the age of 15 years. We believe that these high-signal areas are normal and represent residual hematopoietic marrow.

Original languageEnglish (US)
Pages (from-to)670-676
Number of pages7
JournalPediatric Radiology
Volume36
Issue number7
DOIs
StatePublished - Jul 2006
Externally publishedYes

Fingerprint

Foot Bones
Ankle
Bone Marrow
Foot
Pediatrics
Bone and Bones
Talus
Calcaneus
Fibula
Tibia
Edema

Keywords

  • Bone marrow
  • Feet
  • Hematopoietic marrow
  • High-signal T2 changes
  • MR

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Pediatrics, Perinatology, and Child Health
  • Radiological and Ultrasound Technology

Cite this

Shabshin, N., Schweitzer, M. E., Morrison, W. B., Carrino, J. A., Keller, M. S., & Grissom, L. E. (2006). High-signal T2 changes of the bone marrow of the foot and ankle in children: Red marrow or traumatic changes? Pediatric Radiology, 36(7), 670-676. https://doi.org/10.1007/s00247-006-0129-y

High-signal T2 changes of the bone marrow of the foot and ankle in children : Red marrow or traumatic changes? / Shabshin, Nogah; Schweitzer, Mark E.; Morrison, William B.; Carrino, John A.; Keller, Marc S.; Grissom, Leslie E.

In: Pediatric Radiology, Vol. 36, No. 7, 07.2006, p. 670-676.

Research output: Contribution to journalArticle

Shabshin, N, Schweitzer, ME, Morrison, WB, Carrino, JA, Keller, MS & Grissom, LE 2006, 'High-signal T2 changes of the bone marrow of the foot and ankle in children: Red marrow or traumatic changes?', Pediatric Radiology, vol. 36, no. 7, pp. 670-676. https://doi.org/10.1007/s00247-006-0129-y
Shabshin, Nogah ; Schweitzer, Mark E. ; Morrison, William B. ; Carrino, John A. ; Keller, Marc S. ; Grissom, Leslie E. / High-signal T2 changes of the bone marrow of the foot and ankle in children : Red marrow or traumatic changes?. In: Pediatric Radiology. 2006 ; Vol. 36, No. 7. pp. 670-676.
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AB - Background: High-signal T2-weighted bone marrow changes can be found in both bone marrow edema and hematopoietic marrow and are often seen on pediatric MR images of the feet and ankle. Objective: To evaluate whether high-signal T2 changes of the bone marrow seen on pediatric MRI of feet and ankles represent residual hematopoietic marrow. Materials and methods: A total of 402 bones in 41 pediatric MRI studies of feet and ankles (34 children, 1-18 years) were reviewed by two observers who were blinded to the patients' ages. The studies were reviewed for the presence of high-signal changes of the bone marrow on sagittal fluid-sensitive images. The frequency and location of these foci were correlated with the patients' ages. Results: High-signal T2 changes of the bone marrow were seen in 45/402 bones (11%) and in 24/41 patients younger than 16 years (59%). The changes were most commonly located in the calcaneus (54%), followed by the talus (35%) and navicular bone (35%), invariably at the endosteal surface. In 16 ankles, such foci were seen in the feet but not in the distal tibia/fibula. Symmetric presence (two ankles) or absence (four ankles) of high-signal marrow were seen in six of seven patients with bilateral ankles. Conclusion: High-signal T2 changes of the bone marrow in pediatric feet and ankle MRIs have a symmetric, fairly consistent pattern and disappear after the age of 15 years. We believe that these high-signal areas are normal and represent residual hematopoietic marrow.

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