High-resolution methods for the measurement of scalar coupling constants

Yanqin Lin, Qing Zeng, Liangjie Lin, Zhong Chen, Peter B Barker

Research output: Contribution to journalReview articlepeer-review

Abstract

Scalar couplings provide important information regarding molecular structure and dynamics. The measurement of scalar coupling constants constitutes a topic of interest and significance in NMR spectroscopy. However, the measurement of J values is often not straightforward because of complex signal splitting patterns and signal overlap. Many methods have been proposed for the measurement of scalar coupling constants, both for homonuclear and heteronuclear cases. Different approaches to the measurement of scalar coupling constants are reviewed here with several applications presented. The accurate measurement of scalar coupling constants can greatly facilitate molecular structure elucidation and the study of molecule dynamics.

Original languageEnglish (US)
Pages (from-to)135-159
Number of pages25
JournalProgress in Nuclear Magnetic Resonance Spectroscopy
Volume109
DOIs
StatePublished - Dec 1 2018

Keywords

  • Homonuclear/heteronuclear scalar coupling
  • J-upscaling
  • Nuclear magnetic resonance (NMR)
  • Phase-sensitive J-spectroscopy
  • Selective measurement
  • Spin-state-selective

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Nuclear and High Energy Physics
  • Spectroscopy

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